支气管肺发育不良的 NICU 出院后管理的最新进展。
An update on the post-NICU discharge management of bronchopulmonary dysplasia.
机构信息
Division of Pulmonary Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 11th floor Colket Building, 3501 Civic Center Boulevard, Philadelphia, PA 19446, United States.
Division of Pulmonary Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 11th floor Colket Building, 3501 Civic Center Boulevard, Philadelphia, PA 19446, United States.
出版信息
Semin Perinatol. 2018 Nov;42(7):471-477. doi: 10.1053/j.semperi.2018.09.011. Epub 2018 Oct 2.
Bronchopulmonary dysplasia (BPD) is a chronic lung disease which develops as a result of neonatal/perinatal lung injury. It is the commonest cause of chronic lung disease in infancy and the most frequent morbidity associated with prematurity. The incidence of BPD has continued to rise despite many advances in neonatal care and this increase has been attributed to the increased survival of younger and more premature babies. There have been many advances in the care of patients with early and evolving BPD, yet there is a paucity of data regarding outpatient management of patients with established BPD. There are limited adequately-powered high-quality studies/randomized controlled trials which assess commonly used therapies such as supplemental oxygen, bronchodilators, steroids and diuretics in patients with BPD, beyond short-term effects. Further research is needed to improve our understanding of the role of currently used treatments on the long-term outcomes of patients with established BPD, post-discharge from the neonatal intensive care unit.
支气管肺发育不良(BPD)是一种慢性肺部疾病,由新生儿/围产期肺部损伤引起。它是婴儿期最常见的慢性肺部疾病,也是与早产相关的最常见的发病率。尽管新生儿护理有了许多进步,但 BPD 的发病率仍在持续上升,这归因于更年轻和更早产婴儿的存活率增加。在早期和进展性 BPD 患者的治疗方面已经取得了许多进展,但关于已确诊 BPD 患者的门诊管理的数据却很少。在 BPD 患者中,除了短期效果外,很少有足够大的高质量研究/随机对照试验评估补充氧气、支气管扩张剂、类固醇和利尿剂等常用治疗方法的效果。需要进一步研究以提高我们对目前治疗方法对从新生儿重症监护病房出院后的已确诊 BPD 患者长期结局的作用的认识。