In Vitro Study of the Modulatory Effects of Levofloxacin and BCG on Secretion of Proinflammatory Cytokines in Infiltrative Pulmonary Tuberculosis.

Suppr

超能文献

作者信息

Serebryakova V A, Urazova O I, Novitsky V V, Vengerovskii A I, Kononova T E

机构信息

Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.

出版信息

Bull Exp Biol Med. 2018 Dec;166(2):225-228. doi: 10.1007/s10517-018-4319-z. Epub 2018 Nov 28.

DOI:10.1007/s10517-018-4319-z

PMID:30488211

Abstract

The effects levofloxacin (fluoroquinolone) and vaccinal BCG strain on cytokine production by blood mononuclear leukocytes was studied in patients with infiltrative pulmonary tuberculosis. Combined treatment with levofloxacin and vaccinal BCG strain suppressed the production of TNFα in drug-resistant pulmonary tuberculosis and production of IL-12 and IFNγ in drug-sensitive tuberculosis.

摘要

相似文献

In Vitro Study of the Modulatory Effects of Levofloxacin and BCG on Secretion of Proinflammatory Cytokines in Infiltrative Pulmonary Tuberculosis.

Bull Exp Biol Med. 2018 Dec;166(2):225-228. doi: 10.1007/s10517-018-4319-z. Epub 2018 Nov 28.

CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis.

PLoS One. 2009 Dec 29;4(12):e8459. doi: 10.1371/journal.pone.0008459.

In vitro cellular immune responses to complex and newly defined recombinant antigens of Mycobacterium tuberculosis.

Clin Exp Immunol. 2004 Oct;138(1):139-44. doi: 10.1111/j.1365-2249.2004.02609.x.

Polyfunctional CD4 T-cells correlate with in vitro mycobacterial growth inhibition following Mycobacterium bovis BCG-vaccination of infants.

Vaccine. 2016 Oct 17;34(44):5298-5305. doi: 10.1016/j.vaccine.2016.09.002. Epub 2016 Sep 9.

Mycobacterium tuberculosis Beijing genotype induces differential cytokine production by peripheral blood mononuclear cells of healthy BCG vaccinated individuals.

Immunol Invest. 2012;41(2):144-56. doi: 10.3109/08820139.2011.596604. Epub 2011 Aug 30.

Cytokine production and mRNA expression in pulmonary tuberculosis patients and their household contacts of younger age group (15-25years).

J Immunol Methods. 2016 May;432:65-71. doi: 10.1016/j.jim.2016.02.012. Epub 2016 Feb 12.

Loss of anti-mycobacterial efficacy in mice over time following vaccination with Mycobacterium bovis bacillus Calmette-Guérin.

Vaccine. 2011 Sep 16;29(40):6881-7. doi: 10.1016/j.vaccine.2011.07.051. Epub 2011 Jul 29.

Cytokine profiles in tuberculosis patients and healthy subjects in response to complex and single antigens of Mycobacterium tuberculosis.

FEMS Immunol Med Microbiol. 2006 Jul;47(2):254-61. doi: 10.1111/j.1574-695X.2006.00110.x.

Depressed interleukin-12 production by peripheral blood mononuclear cells after in vitro stimulation with the 30-kDa antigen in recurrent pulmonary tuberculosis patients.

Med Microbiol Immunol. 2003 May;192(2):61-9. doi: 10.1007/s00430-002-0117-2. Epub 2002 Oct 31.

Recombinant bacille Calmette-Guerin coexpressing Ag85b, CFP10, and interleukin-12 elicits effective protection against Mycobacterium tuberculosis.

J Microbiol Immunol Infect. 2017 Feb;50(1):90-96. doi: 10.1016/j.jmii.2014.11.019. Epub 2014 Dec 11.

引用本文的文献

Immunomodulatory Effects of Fluoroquinolones in Community-Acquired Pneumonia-Associated Acute Respiratory Distress Syndrome.

Biomedicines. 2024 Mar 29;12(4):761. doi: 10.3390/biomedicines12040761.

Clinical Efficacy of Chemotherapy Regimen Combined with Levofloxacin in Patients with Pulmonary Tuberculosis Complicated with Type-2 Diabetes.

Pak J Med Sci. 2023 Mar-Apr;39(2):444-449. doi: 10.12669/pjms.39.2.6364.

Repurposing Immunomodulatory Drugs to Combat Tuberculosis.

Front Immunol. 2021 Apr 13;12:645485. doi: 10.3389/fimmu.2021.645485. eCollection 2021.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验