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2018 年膳食谷氨酸工作组介绍及总结。

Introduction and Summary of the 2018 Dietary Glutamate Workshop.

机构信息

Hôpital Cochin, Service de Biochimie, and Faculté de Pharmacie, Université Paris Descartes, Paris, France,

Department of Psychiatry and Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

出版信息

Ann Nutr Metab. 2018;73 Suppl 5:1-4. doi: 10.1159/000494775. Epub 2018 Dec 3.

Abstract

The 2018 Dietary Glutamate Workshop was organized and sponsored by the International Glutamate Technical Committee to provide a platform for a broad expert discussion on all relevant aspects of glutamate metabolism and safety in human nutrition. The participants reached a consensus with previous safety evaluations conducted by the global expert bodies, but contradicted the 2017 re-evaluation of dietary glutamates by the European Food Safety Authority, which proposed a group acceptable daily intake (ADI) of 30 mg/kg body weight per day. The participants of the Workshop concluded that the present knowledge on metabolism, kinetics, developmental and general toxicity of dietary glutamates did not warrant a change in the previous ADI of "not specified."

摘要

2018 年膳食谷氨酸工作组由国际谷氨酸技术委员会组织和赞助,旨在为广泛的专家讨论提供一个平台,内容涉及人类营养中谷氨酸代谢和安全性的所有相关方面。与会者与全球专家机构以前进行的安全性评估达成了共识,但与欧洲食品安全局 2017 年对膳食谷氨酸的重新评估结果相悖,欧洲食品安全局提出了每日 30 毫克/公斤体重的可接受的每日摄入量 (ADI)。工作组的与会者得出结论,目前关于膳食谷氨酸的代谢、动力学、发育和一般毒性的知识并没有证明需要改变之前的“未指定”ADI。

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