Faden Asma'a, Aljamili Alaa, Aljamili Anfal, Alahmari Sumayyah, Asiri Abdulrahman
Department of Oral Medicine, King Saud University College of Dentistry, Riyadh, Saudi Arabia.
Department of Family Medicine Resident, Ministry of Health, Riyadh, Saudi Arabia.
Int J Health Sci (Qassim). 2018 Nov-Dec;12(6):65-68.
Mixed connective tissue disease (MCTD) or overlap syndrome is a rare disease. It has overlapping features of more than one autoimmune disease with high titer of anti-ribonucleoprotein antibodies against U1. We present a 12-year-old Saudi male patient who was presented to the dental clinic complaining from non-healing oral ulcers and multiple periapical abscesses that not responsive to extractions and the use of oral antibiotics, these symptoms were accompanied with persistent fever, headache, muscle weakness, general malaise, and painful bilateral cervical lymphadenopathy. After a thorough investigation, he was diagnosed with (MCTD) and was managed dentally and medically accordingly.
混合性结缔组织病(MCTD)或重叠综合征是一种罕见疾病。它具有不止一种自身免疫性疾病的重叠特征,伴有高滴度的抗U1核糖核蛋白抗体。我们报告一名12岁的沙特男性患者,他因口腔溃疡不愈合和多处根尖周脓肿就诊于牙科诊所,这些症状对拔牙和口服抗生素治疗均无反应,同时伴有持续发热、头痛、肌肉无力、全身不适以及双侧颈部疼痛性淋巴结病。经过全面检查,他被诊断为混合性结缔组织病,并据此进行了牙科和医学治疗。