Cutaneous malignant melanoma of the oral cavity following skin graft reconstruction: Case report.
作者信息
Mayo Zachary, Seyedin Steven, Marquardt Michael, Mohiuddin Imran, Milhem Mohammed, Liu Vincent, Pagedar Nitin, Anderson Carryn
机构信息
Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Department of Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
出版信息
Head Neck. 2019 Feb;41(2):E26-E29. doi: 10.1002/hed.25417. Epub 2018 Dec 7.
BACKGROUND
Malignant melanomas on skin graft recipient sites are rare, with few cases reported in the literature.
METHODS
We present a case report of a patient with recurrent cutaneous melanoma in the grafted anterolateral thigh flap of the tongue.
RESULTS
A patient underwent hemiglossectomy with free flap reconstruction for squamous cell carcinoma of the tongue. Five years later the patient was seen with a 1-cm nodule and surrounding erythroplakia at the recipient site of the graft. Analysis revealed cutaneous malignant melanoma. Patient then related a remote history of a suspected skin melanoma of the donor leg that had been treated with excision, with unknown histology.
CONCLUSION
This may be the first reported case of a cutaneous malignant melanoma in the oral cavity following an anterolateral thigh free flap reconstruction, emphasizing the importance of obtaining a comprehensive history of skin cancers and closely inspecting the donor site prior to graft harvesting.
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