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代谢综合征患者二尖瓣修复术后肺部感染的特征及其与血压、血糖和血脂的关系。

Characteristics of pulmonary infection after mitral valve repair in patients with metabolic syndrome and its relationship with blood pressure, blood glucose and blood lipid.

作者信息

Xiao Peng, Song Wei, Han Zhe

机构信息

Department of Thoracic Surgery, Luoyang Center Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.

Department of Cardiac Surgery, The Second People's Hospital of Liaocheng, Linqing, Shandong 252600, P.R. China.

出版信息

Exp Ther Med. 2018 Dec;16(6):5003-5008. doi: 10.3892/etm.2018.6839. Epub 2018 Oct 9.

Abstract

Characteristics of pulmonary infection after mitral valve repair in patients with metabolic syndrome (MS) and its relationships with blood pressure, blood glucose and blood lipid were investigated. Clinical data of 126 patients were retrospectively analyzed, and patients were divided into infection group (n=19) and non-infection group (n=107). The differences of MS components in patients between the two groups were compared, and the distribution of pathogens and related factors of pulmonary infection were analyzed. The postoperative pulmonary infection rate was 15.08% (19/126); the body mass index (BMI), blood pressure, fasting blood glucose (FBG), triglyceride, total cholesterol, low-density lipoprotein cholesterol, the extubation time of trachea cannula, ventilator use time, rethoracotomy hemostasis rate, sternal dehiscence rate and incidence of low-cardiac-output syndrome were higher and high-density lipoprotein (HDL-C), left ventricular ejection fraction (LVEF) was lower in the infection group than that in the non-infection group (p<0.05). The rate of postoperative pulmonary infection in patients with MS was higher than in those without MS (p<0.05). Cardiac function, BMI, FBG, HDL-C, LVEF value, extubation time of trachea cannula, ventilator use time, sternal dehiscence, rethoracotomy hemostasis and low-cardiac-output syndrome were independent risk factors for pulmonary infection after mitral valve repair in patients with MS. In conclusion, pulmonary infection easily occurs in patients with MS after mitral valve repair. Taking intervention measures according to the characteristics of pulmonary infection pathogens and predisposing factors is expected to reduce the incidence of pulmonary infection.

摘要

研究代谢综合征(MS)患者二尖瓣修复术后肺部感染的特征及其与血压、血糖和血脂的关系。回顾性分析126例患者的临床资料,将患者分为感染组(n = 19)和非感染组(n = 107)。比较两组患者MS各组分的差异,分析肺部感染的病原菌分布及相关因素。术后肺部感染率为15.08%(19/126);感染组患者的体重指数(BMI)、血压、空腹血糖(FBG)、甘油三酯、总胆固醇、低密度脂蛋白胆固醇、气管插管拔管时间、呼吸机使用时间、再次开胸止血率、胸骨裂开率及低心排血量综合征发生率均高于非感染组,而高密度脂蛋白(HDL-C)、左心室射血分数(LVEF)低于非感染组(p<0.05)。MS患者术后肺部感染率高于无MS患者(p<0.05)。心功能、BMI、FBG、HDL-C、LVEF值、气管插管拔管时间、呼吸机使用时间、胸骨裂开、再次开胸止血及低心排血量综合征是MS患者二尖瓣修复术后肺部感染的独立危险因素。综上所述,MS患者二尖瓣修复术后易发生肺部感染。根据肺部感染病原菌特点及易感因素采取干预措施有望降低肺部感染发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/426f/6257412/a885687e80bb/etm-16-06-5003-g00.jpg

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