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精神分裂症患者对幻觉的感知是否异常?

Is the perception of illusions abnormal in schizophrenia?

机构信息

Laboratory of Psychophysics, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Switzerland; Allgemeine und Experimentelle Psychologie, Department Psychologie, Ludwig-Maximilians-Universität München (LMU), Leopoldstraße 13, München 80802 Germany.

Laboratory of Vision Physiology, Beritashvili Centre of Experimental Biomedicine, Tbilisi, Georgia; Institute of Cognitive Neurosciences, Free University of Tbilisi, Tbilisi, Georgia.

出版信息

Psychiatry Res. 2018 Dec;270:929-939. doi: 10.1016/j.psychres.2018.10.063. Epub 2018 Oct 30.

Abstract

There seems to be no common factor for visual perception, i.e., performance in visual tasks correlates only weakly with each other. Similar results were found with visual illusions. One may expect common visual factors for individuals suffering from pathologies that alter brain functioning, such as schizophrenia. For example, patients who are more severely affected by the disease, e.g., stronger positive symptoms, may show increased illusion magnitudes. Here, in the first experiment, we used a battery of seven visual illusions and a mental imagery questionnaire. Illusion magnitudes for the seven illusions did not differ significantly between the patients and controls. In addition, correlations between the different illusions and mental imagery were low. In the second experiment, we tested 59 patients (mostly outpatients) with ten visual illusions. As for the first experiment, patients and controls showed similar susceptibility to all but one visual illusion. Moreover, there were no significant correlations between different illusions, symptoms, or medication type. Thus, it seems that perception of visual illusions is mostly intact in schizophrenia.

摘要

似乎没有共同的视觉感知因素,即视觉任务的表现彼此之间相关性很弱。视觉错觉也得到了类似的结果。人们可能期望患有改变大脑功能的疾病(如精神分裂症)的个体有共同的视觉因素。例如,受疾病影响更严重的患者,例如阳性症状更强,可能会表现出更大的错觉幅度。在这里,在第一个实验中,我们使用了一套七种视觉错觉和一种心理意象问卷。七种错觉的错觉幅度在患者和对照组之间没有显著差异。此外,不同错觉与心理意象之间的相关性较低。在第二个实验中,我们测试了 59 名患者(大多数为门诊患者)的十种视觉错觉。与第一个实验一样,患者和对照组对除一种错觉以外的所有错觉都表现出相似的易感性。此外,不同错觉、症状或药物类型之间没有显著相关性。因此,精神分裂症患者的视觉错觉感知似乎基本完整。

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