接受恩替卡韦治疗效果欠佳患者中致癌性增强的乙型肝炎病毒X基因变异体的出现 - Suppr

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超能文献

Emergence of Oncogenic-Enhancing Hepatitis B Virus X Gene Mutants in Patients Receiving Suboptimal Entecavir Treatment.

作者信息

Lin Chih-Lang, Chu Yu-De, Yeh Chau-Ting

机构信息

Liver Research Unit, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.

Community Medicine Research Center, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.

出版信息

Hepatology. 2019 May;69(5):2292-2296. doi: 10.1002/hep.30423. Epub 2019 Feb 14.

DOI:10.1002/hep.30423

PMID:30552766

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6644294/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6383/6644294/87a15cf3402f/HEP-69-2292-g001.jpg

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本文引用的文献

Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients.

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The risk of hepatocellular carcinoma decreases after the first 5 years of entecavir or tenofovir in Caucasians with chronic hepatitis B.

Hepatology. 2017 Nov;66(5):1444-1453. doi: 10.1002/hep.29320. Epub 2017 Oct 11.

X region mutations of hepatitis B virus related to clinical severity.

World J Gastroenterol. 2016 Jun 28;22(24):5467-78. doi: 10.3748/wjg.v22.i24.5467.

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Emergence of Oncogenic-Enhancing Hepatitis B Virus X Gene Mutants in Patients Receiving Suboptimal Entecavir Treatment.

作者信息

Lin Chih-Lang, Chu Yu-De, Yeh Chau-Ting

机构信息

Liver Research Unit, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.

Community Medicine Research Center, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.

出版信息

Hepatology. 2019 May;69(5):2292-2296. doi: 10.1002/hep.30423. Epub 2019 Feb 14.

DOI:10.1002/hep.30423

PMID:30552766

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6644294/

Abstract

摘要