前庭神经鞘瘤患者与症状性结局相关的生活质量：加拿大中心视角
Quality of life related to symptomatic outcomes in patients with vestibular schwannomas: A Canadian Centre perspective.
作者信息
Hebb Andrea L O, Erjavec Niki, Morris David P, Mulroy Liam, Bance Manohar, Shoman Nael, Walling Simon
机构信息
Division of Neurosurgery, QEII Halifax Infirmary Site, 3rd Floor, 1796 Summer Street, Halifax, NS B3H 3A7, Canada; Maritime Lateral Skull Base Clinic: Divisions of Neurosurgery, OtolaryngologyHead & Neck Surgery, Canada; Department of Radiation Oncology, Dalhousie University, QEII Health Sciences Centre, 3rd floor Dickson Building, 5820 University Avenue, Halifax, NS B3H 1Y9, Canada.
Division of Neurosurgery, QEII Halifax Infirmary Site, 3rd Floor, 1796 Summer Street, Halifax, NS B3H 3A7, Canada; Maritime Lateral Skull Base Clinic: Divisions of Neurosurgery, OtolaryngologyHead & Neck Surgery, Canada; Department of Radiation Oncology, Dalhousie University, QEII Health Sciences Centre, 3rd floor Dickson Building, 5820 University Avenue, Halifax, NS B3H 1Y9, Canada.
出版信息
Am J Otolaryngol. 2019 Mar-Apr;40(2):236-246. doi: 10.1016/j.amjoto.2018.11.004. Epub 2018 Nov 22.
Patients with vestibular schwannomas (VS) typically present with hearing loss and tinnitus as well as variable cranial nerve dysfunctions. Surgical resection, stereotactic radiotherapy and/or conservative management employing serial magnetic resonance or computed tomography imaging serve as the main treatment options. Quality of life (QoL) may be impacted by the extent of tumour burden and exacerbated or relieved by treatment. Subjective assessment and quality of life inventories provide valuable information in client centered approaches with important implications for treatment. The intention of QoL measurements affecting VS patients within a clinical setting is to facilitate discussions regarding treatment options and objectively evaluate patient- centered clinical outcomes in a naturalistic setting.
前庭神经鞘瘤（VS）患者通常表现为听力丧失、耳鸣以及各种颅神经功能障碍。手术切除、立体定向放射治疗和/或采用系列磁共振成像或计算机断层扫描成像的保守治疗是主要的治疗选择。生活质量（QoL）可能会受到肿瘤负荷程度的影响，治疗可能会使其加重或缓解。主观评估和生活质量量表在以患者为中心的方法中提供了有价值的信息，对治疗具有重要意义。在临床环境中测量影响VS患者的生活质量的目的是促进关于治疗选择的讨论，并在自然环境中客观评估以患者为中心的临床结果。
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