中国儿科药学发展及儿科药学专家研究领域的系统评价方案

Protocol for a systematic evaluation of pediatric pharmacy development and pediatric pharmacy experts' research area in China.

作者信息

Li Hao, Huang Shi-Ying, Zhang Shun-Guo, Chen Min-Ling, Gu Zhi-Chun, Shi Fang-Hong

机构信息

Department of Pharmacy, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai.

Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.

出版信息

Medicine (Baltimore). 2018 Dec;97(50):e13597. doi: 10.1097/MD.0000000000013597.

DOI:10.1097/MD.0000000000013597

PMID:30558032

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6320144/

Abstract

BACKGROUND

The pediatric pharmacy research status of children's hospitals in China is still unknown. Our previous findings suggest the regional differences in academic level in tertiary (grade III level A) children's hospitals in China.

METHODS

This systemic evaluation described in this protocol will be conducted to follow the Cochrane Handbook. We will perform a systemic literature search of relevant databases including Chinese databases (CNKI, Wanfang Data, VIP Paper Check System) and English databases (Medline, EMbase, Cochrane Library) from inception to December 31, 2018. The search strategy will be enacted according to the guidance offered from the Cochrane Handbook. Two rounds of searches will be conducted to prevent the omission of relevant literature. A pre-set grading standard will be used to give calculation weight (W) to evaluate the quality of each article. Data synthesis will be performed using STATA software (version 13.1, Statacorp, College Station, Texas). Pediatric pharmacy development index (PPDI) of each hospital will be used to evaluate the pediatric pharmacy development in each tertiary children's hospitals. The cumulative calculation weight (∑W) and annual calculation weight (∑yearW) will be used to evaluate the academic level of pharmaceutical departments in different tertiary children's hospitals. Subgroup analysis will be performed to compare the number of different types of articles published between different hospitals base on different research areas such as policy research, basic research, and clinical research.

RESULTS

In this article, we will evaluate pediatric pharmacy development and the research area of pediatric pharmacy experts in China. Based on the results from this research, we will analyze the professional backgrounds of pediatric pharmacy experts from 23 tertiary children's hospitals in China. According to the contents and research directions of literature published by the pediatric pharmacy experts in these 23 hospitals, we will determine the professional field of pediatric pharmacy experts and establish an expert database. In the process of formulating the related national or local policies in the future, the expert database will be selected accurately to reach the expert consensus.

CONCLUSION

Our study will provide a comprehensive picture of pediatric pharmacy development in China. The pediatrics pharmacy expert's database constructed by this study will be used to build consensus on pediatric pharmacology in the future.

摘要

背景

中国儿童医院的儿科药学研究现状仍不明确。我们之前的研究结果表明中国三级甲等儿童医院在学术水平上存在地区差异。

方法

本方案中描述的这项系统评价将按照Cochrane手册进行。我们将对相关数据库进行系统的文献检索，包括中国数据库（中国知网、万方数据、维普论文检测系统）和英文数据库（Medline、EMbase、Cochrane图书馆），检索时间从建库至2018年12月31日。检索策略将根据Cochrane手册提供的指导制定。将进行两轮检索以防止遗漏相关文献。将使用预设的分级标准赋予计算权重（W）以评估每篇文章的质量。将使用STATA软件（版本13.1，Statacorp公司，德克萨斯州大学城）进行数据合成。每家医院的儿科药学发展指数（PPDI）将用于评估各三级儿童医院的儿科药学发展情况。累积计算权重（∑W）和年度计算权重（∑yearW）将用于评估不同三级儿童医院药学部门的学术水平。将进行亚组分析，以比较不同医院基于政策研究、基础研究和临床研究等不同研究领域发表的不同类型文章的数量。

结果

在本文中，我们将评估中国儿科药学的发展以及儿科药学专家的研究领域。基于本研究的结果，我们将分析中国23家三级儿童医院儿科药学专家的专业背景。根据这23家医院儿科药学专家发表文献的内容和研究方向，我们将确定儿科药学专家的专业领域并建立专家数据库。在未来制定相关国家或地方政策的过程中，将准确选取专家数据库以达成专家共识。