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真实世界中的左心室心内膜起搏:单中心五年经验

Left ventricular endocardial pacing in the real world: Five years of experience at a single center.

作者信息

García Guerrero Juan J, Fernández de la Concha Castañeda Joaquín, Doblado Calatrava Manuel, Redondo Méndez Ángel, Lázaro Medrano Manuel, Merchán Herrera Antonio

机构信息

Department of Cardiology, Hospital Infanta Cristina, Badajoz, Spain.

出版信息

Pacing Clin Electrophysiol. 2019 Feb;42(2):153-160. doi: 10.1111/pace.13591. Epub 2019 Jan 14.

Abstract

BACKGROUND

A left ventricular (LV) endocardial lead implant to achieve cardiac resynchronization therapy (CRT) is feasible when a conventional implant failed due to anatomical or technical issues or when the venous implant was performed but the patient did not respond to the therapy.

METHODS

Data about the implantation procedure (age, sex, clinical characteristics, anticoagulant use, and previous devices), patient characteristics (indication, technique used, lead model, complications), and follow-up (clinical and echocardiographic outcome, LV lead electrical measurements) were analyzed for all CRT systems implanted using LV endocardial lead, due to failed conventional implant or nonresponse, between April 2011 and November 2016.

RESULTS

Thirty-five patients were implanted with an active fixation LV endocardial lead during the study period, without significant complications. There were no dislodgements or severe complications related to the implant procedure in the follow-up period (36 ± 20 months) and a high percentage of patients responded to therapy, as assessed by several indicators.

CONCLUSIONS

An LV endocardial lead implant was feasible when the conventional technique had previously failed or was not effective. A high rate of response was achieved without any significant complications.

摘要

背景

当传统植入因解剖或技术问题失败,或已进行静脉植入但患者对治疗无反应时,植入左心室(LV)心内膜导线以实现心脏再同步治疗(CRT)是可行的。

方法

分析了2011年4月至2016年11月期间,所有因传统植入失败或无反应而使用LV心内膜导线植入CRT系统的患者的植入过程数据(年龄、性别、临床特征、抗凝剂使用情况和既往器械)、患者特征(适应症、使用的技术、导线型号、并发症)以及随访情况(临床和超声心动图结果、LV导线电测量)。

结果

在研究期间,35例患者植入了主动固定LV心内膜导线,无明显并发症。在随访期(36±20个月)内,未发生与植入过程相关的导线移位或严重并发症,且通过多项指标评估,有很高比例的患者对治疗有反应。

结论

当传统技术先前失败或无效时,植入LV心内膜导线是可行的。实现了高反应率且无任何明显并发症。

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