Barabas Arpad, Cole Chad, Kovacs Zoltan, Kovacs Erno, Lafreniere Rene
Department of Surgery, University of Calgary, Calgary, AB T2N 1N4, Canada.
Department of Neurosurgery, University of Utah, Salt Lake City, Utah, UT 84112, USA.
Vaccines (Basel). 2018 Dec 21;7(1):1. doi: 10.3390/vaccines7010001.
In addition to active and passive immunizations, there is a third method of immunization, the modified vaccination technique, which is based on injecting a combination of target antigens and antibodies against this antigen. The vaccine is essentially comprised of immune complexes with pre-determined immune-inducing components. When such an immune complex (target antigen × antibody against the target antigen) with a slight antigen excess is administered, it evokes a corrective immune response by the production of the same antibody with the same specificity against the target antigen that is present in the immune complex (pre-determined immune response).
除了主动免疫和被动免疫之外,还有第三种免疫方法,即改良疫苗接种技术,该技术基于注射靶抗原和针对该抗原的抗体的组合。疫苗本质上由具有预先确定的免疫诱导成分的免疫复合物组成。当给予这种具有轻微抗原过量的免疫复合物(靶抗原×针对靶抗原的抗体)时,它会通过产生与免疫复合物中存在的针对靶抗原具有相同特异性的相同抗体来引发纠正性免疫反应(预先确定的免疫反应)。