Shimizu Junya, Yoshimoto Mitsunori, Takebayashi Tsuneo, Terashima Yoshinori, Yamashita Toshihiko
Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
J Orthop Case Rep. 2018 May-Jun;8(3):7-9. doi: 10.13107/jocr.2250-0685.1084.
Anaerobic vertebral osteomyelitis has been reported rarely. In this report, we describe an extremely rare case of a patient who suffered from vertebral osteomyelitis caused by Peptostreptococcus micros.
A 73-year-old man with a history of diabetes mellitus was admitted to our hospital with a 5-month history of severe low back pain. A radiograph of the lumbar spine demonstrated intervertebral disc space narrowing with indistinct end plates at the L3-L4 level. T2-weighted magnetic resonance image showed high signal intensity at L3-L4 intervertebral disc space. We suspected pyogenic spondylitis and performed percutaneous posterolateral endoscopic debridement. The results of intraoperative sample cultures were positive for P. micros, an anaerobic Gram-positive coccus. He was treated by the antibiotic therapy. Low back pain resolved and his white blood cell count and C-reactive protein levels remained normal with the combination therapy. During 2-year follow-up, he reported no low back pain and had no signs of infection recurrence.
If a patient who was in immunodepression status develops severe back pain, the clinician should be suspicious of the possibility of spondylitis by P. micros and start antibiotic therapy after undergoing sample collection.
厌氧性椎体骨髓炎鲜有报道。在本报告中,我们描述了一例极为罕见的由微小消化链球菌引起的椎体骨髓炎患者。
一名有糖尿病病史的73岁男性因严重腰痛5个月入住我院。腰椎X线片显示L3-L4水平椎间盘间隙变窄,终板模糊。T2加权磁共振图像显示L3-L4椎间盘间隙信号增强。我们怀疑是化脓性脊柱炎并进行了经皮后外侧内镜清创术。术中样本培养结果显示微小消化链球菌呈阳性,这是一种厌氧革兰氏阳性球菌。他接受了抗生素治疗。联合治疗后,腰痛缓解,白细胞计数和C反应蛋白水平保持正常。在2年的随访中,他报告无腰痛,也没有感染复发的迹象。
如果处于免疫抑制状态的患者出现严重背痛,临床医生应怀疑微小消化链球菌引起脊柱炎的可能性,并在采集样本后开始抗生素治疗。