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杂交足静脉动脉化治疗无选择肢端缺血患者:初步报告。

Hybrid Foot Vein Arterialization in No-Option Patients With Critical Limb Ischemia: A Preliminary Report.

机构信息

1 Peripheral Interventional Unit, Humanitas Gavazzeni, Bergamo, Italy.

2 Vascular Unit, Humanitas Gavazzeni, Bergamo, Italy.

出版信息

J Endovasc Ther. 2019 Feb;26(1):7-17. doi: 10.1177/1526602818820792. Epub 2018 Dec 28.

Abstract

PURPOSE

To describe a preliminary experience in treating no-option critical limb ischemia (CLI) patients with a hybrid foot vein arterialization (HFVA) technique combining open plus endovascular approaches.

MATERIALS AND METHODS

Between May 2016 and January 2018, 35 consecutive patients (mean age 68±12 years; 28 men) with 36 no-option CLI limbs underwent HFVA in our center. All limbs had grade 3 WIfI (Wound, Ischemia, and foot Infection) ischemia, and the wound classification was grade 1 in 4 (11%) limbs, grade 2 in 4 (11%), and grade 3 in 28 (78%). Surgical bypass was done on the medial marginal vein or a posterior tibial vein, followed by endovascular removal of foot vein valves and embolization of foot vein collaterals. A "tension-free" surgical approach was used to treat foot lesions.

RESULTS

At a mean follow-up of 10.8±2 months, limb salvage was achieved in 25 (69%) limbs and wound healing in 16 (44%); 9 patients presented an unhealed wound. Eleven (31%) patients underwent a major amputation (2 below the knee and 9 thigh). One patient with an unhealed wound and open bypass died of myocardial infarction.

CONCLUSION

HFVA is a promising technique able to achieve acceptable rates of limb salvage and wound healing in no-option patients generally considered candidates for an impending major amputation. Further studies are needed to standardize the technique and better identify patients who can benefit from this approach.

摘要

目的

描述一种结合开放加血管内技术的混合足部静脉动脉化(HFVA)技术治疗无选择的严重肢体缺血(CLI)患者的初步经验。

材料和方法

在 2016 年 5 月至 2018 年 1 月期间,我们中心对 35 例连续的 36 例无选择 CLI 肢体的患者进行了 HFVA。所有肢体均存在 3 级 WIfI(伤口、缺血和足部感染)缺血,其中 4 例(11%)肢体的伤口分级为 1 级,4 例(11%)肢体的伤口分级为 2 级,28 例(78%)肢体的伤口分级为 3 级。在内侧缘静脉或胫后静脉上进行旁路手术,然后进行血管内足部静脉瓣膜切除和足部静脉侧支栓塞。采用“无张力”手术方法治疗足部病变。

结果

在平均 10.8±2 个月的随访中,25 例(69%)肢体保肢成功,16 例(44%)伤口愈合;9 例患者伤口未愈合。11 例(31%)患者进行了大截肢(2 例膝下截肢,9 例大腿截肢)。1 例未愈合伤口和开放旁路的患者因心肌梗死死亡。

结论

HFVA 是一种有前途的技术,能够在通常被认为即将进行大截肢的无选择患者中实现可接受的肢体保肢率和伤口愈合率。需要进一步的研究来规范该技术,并更好地识别能够从该方法中获益的患者。

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