红斑狼疮中Clq结合活性：与“狼疮带试验”的相关性
Clq binding activity in lupus erythematosus: correlation with the "lupus band test".
作者信息
Tappeiner G, O'Loughlin S, Jordon R E
出版信息
J Invest Dermatol. 1978 Apr;70(4):187-90. doi: 10.1111/1523-1747.ep12541308.
A 131I C1q binding assay was employed to estimate C1q binding activity (C1q BA), presumably due to the presence of circulating immune complexes, in lupus erythematosus sera. Thirteen of 16 sera from patients with systemic lupus erythematosus (SLE) had elevated C1q BA. Only 1 of 17 sera from patients with generalized discoid LE (GDLE) and none of 5 localized DLE patient's sera had elevated C1q BA. A correlation between a positive LE band test and the level of C1q BA was apparent. A positive LE band test tended to occur in patients with higher levels of C1q BA, whereas a negative LE band test tended to occur in patients with low levels of C1q BA.
采用¹³¹I C1q结合试验来评估红斑狼疮患者血清中可能由于循环免疫复合物存在而产生的C1q结合活性（C1q BA）。16例系统性红斑狼疮（SLE）患者的血清中有13例C1q BA升高。17例泛发性盘状红斑狼疮（GDLE）患者的血清中只有1例C1q BA升高，5例局限性盘状红斑狼疮（DLE）患者的血清中无一例C1q BA升高。LE带试验阳性与C1q BA水平之间存在明显相关性。C1q BA水平较高的患者倾向于出现LE带试验阳性，而C1q BA水平较低的患者倾向于出现LE带试验阴性。
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