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导航引导下的内镜检查联合深部外侧眶切开术治疗眶尖外侧小肿瘤

Navigation-Guided Endoscopy Combined with Deep Lateral Orbitotomy for Removal of Small Tumors at the Lateral Orbital Apex.

作者信息

Zhou GuangMing, Ju Xin, Yu Bo, Tu YunHai, Shi JieLiang, Wu EnDe, Wu WenCan

机构信息

Minimally Invasive Surgical Center, The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

出版信息

J Ophthalmol. 2018 Nov 25;2018:2827491. doi: 10.1155/2018/2827491. eCollection 2018.

Abstract

PURPOSE

To evaluate the efficacy, feasibility, and safety of the navigation-guided endoscopy combined with deep lateral orbitotomy for removal of small tumors at the lateral orbital apex.

DESIGN

A retrospective, noncomparative case series.

METHODS

Retrospective analysis of ten patients (10 eyes) with small tumors at the lateral orbital apex comprised navigation-guided endoscopy combined with deep lateral orbitotomy at the Eye Hospital of Wenzhou Medical University from November 2015 to November 2017. In each case, the indication of surgery was existing or imminent visual impairment due to the tumor. The removal was believed to be complete if the mass was removed intactly during the surgery. The tumor character was confirmed by pathological examination after surgery. Patients were followed up to 3 months after surgery. Best corrected visual acuity before and after surgery was compared.

RESULTS

All tumors were completely removed by the navigation-guided endoscopic approach. The mean preoperative best corrected visual acuity was 6/15 (95% confidence interval (95% CI) 6/40-6/8.5), and the mean postoperative best corrected visual acuity was 6/10 (95% CI 6/15-6/7.5). 5 of 7 (71%) patients with vision loss gained visual improvement in different degrees after surgery, and the rest of the patients had preoperative best corrected visual acuity. Visual field of all patients also improved. 8 cavernous hemangiomas and 2 schwannomas were confirmed postoperatively by pathology. 4 patients accompanied with limitation of eye abduction, which recovered spontaneously in an average of 4 weeks. No other serious complications occurred.

CONCLUSIONS

Navigation-guided endoscopy combined with deep lateral orbitotomy seems to be a feasible, efficient, and safe approach for removing small tumors at the lateral orbital apex. This trial is registered with ChiCTR1800019244.

摘要

目的

评估导航引导下内镜联合外侧眶深部切开术切除眶尖外侧小肿瘤的疗效、可行性及安全性。

设计

一项回顾性、非对照病例系列研究。

方法

回顾性分析2015年11月至2017年11月在温州医科大学附属眼视光医院接受导航引导下内镜联合外侧眶深部切开术治疗的10例(10只眼)眶尖外侧小肿瘤患者。每例患者的手术指征均为肿瘤导致的现有或即将出现的视力损害。若手术中肿瘤完整切除,则认为切除彻底。术后通过病理检查确定肿瘤性质。对患者进行术后3个月的随访。比较手术前后的最佳矫正视力。

结果

所有肿瘤均通过导航引导下的内镜手术方法完整切除。术前平均最佳矫正视力为6/15(95%置信区间[95%CI]6/40 - 6/8.5),术后平均最佳矫正视力为6/10(95%CI 6/15 - 6/7.5)。7例视力丧失患者中有5例(71%)术后视力有不同程度改善,其余患者保持术前最佳矫正视力。所有患者的视野也有所改善。术后病理确诊8例海绵状血管瘤和2例神经鞘瘤。4例患者伴有眼球外展受限,平均4周后自行恢复。未发生其他严重并发症。

结论

导航引导下内镜联合外侧眶深部切开术似乎是一种切除眶尖外侧小肿瘤的可行、有效且安全的方法。本试验在中国临床试验注册中心注册号为ChiCTR1800019244。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a14e/6286765/f8e26e3dd29c/JOPH2018-2827491.001.jpg

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