1 Division of Family Medicine, National Yang-Ming University Hospital, Yilan, Taiwan.
2 Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
J Palliat Med. 2019 Feb;22(2):188-192. doi: 10.1089/jpm.2018.0299. Epub 2019 Jan 2.
Hemodialysis (HD) is the most common renal replacement therapy for patients with end-stage renal disease in Taiwan. The use of HD in hospice care and its impact on terminal cancer patients remains unclear.
Using claim data from the Taiwan National Health Insurance Research Database, all patients who died from cancer and claim data of their terminal admissions in hospice from 2007 to 2010. Those with a comorbid diagnosis of renal failure or who had health insurance claims data for HD were enrolled.
A total of 5482 subjects were identified, of whom 4484 received HD and 998 did not. The HD group was significantly correlated with a younger age and high costs of terminal hospice admission. After adjusting for age and gender, the HD group was positively associated with a long hospice stay, in-hospice death, bone/connective tissue/breast cancers, and secondary/metastatic cancers, but negatively associated with genitourinary cancer. Compared with Department of Health/municipal hospitals, patients at both national and private university-affiliated hospitals were less likely to undergo HD.
For terminal cancer patients under hospice care, HD was associated with a younger age, long terminal hospice stay, and high medical costs. Some types of cancers were associated with HD. University-affiliated hospitals played significant roles in non-HD renal supportive care. In-hospice HD is still common in Taiwan. Dialysis withdrawal and alternative care have space to promoting in hospice care.
血液透析(HD)是中国台湾地区终末期肾病患者最常用的肾脏替代治疗方法。在临终关怀中使用 HD 以及其对晚期癌症患者的影响尚不清楚。
利用来自中国台湾全民健康保险研究数据库的理赔数据,纳入所有因癌症死亡且在临终关怀期间入住的末期住院患者,同时纳入患有肾衰竭的合并症诊断或有 HD 医疗保险理赔数据的患者。
共纳入 5482 名患者,其中 4484 名患者接受了 HD,998 名患者未接受 HD。HD 组与年龄较小和临终关怀入院的高费用显著相关。在调整年龄和性别后,HD 组与较长的临终关怀停留时间、临终关怀院内死亡、骨/结缔组织/乳腺癌和继发性/转移性癌症呈正相关,但与泌尿生殖系统癌症呈负相关。与卫生署/市立医院相比,国立和私立大学附属医院的患者接受 HD 的可能性较小。
对于接受临终关怀的晚期癌症患者,HD 与年龄较小、临终关怀停留时间较长和医疗费用较高相关。某些类型的癌症与 HD 相关。附属医院在非 HD 肾脏支持治疗方面发挥了重要作用。临终关怀中的 HD 仍很常见。在临终关怀中推广透析退出和替代治疗仍有空间。