Neuromuscular Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman.
Human Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman.
J Geriatr Phys Ther. 2019 Oct/Dec;42(4):E55-E61. doi: 10.1519/JPT.0000000000000219.
Previous literature suggests that reductions in appendicular skeletal mass (ASM) may have a greater detrimental effect than total lean body mass regarding the onset and progression of sarcopenia. Unfortunately, limited access to equipment that accurately determines ASM often leads to many individuals remaining undiagnosed and experiencing functional decline. Therefore, the purpose of this investigation was to determine the ability of functional and neuromuscular measures to identify ASM in older women.
Forty-one (sarcopenic n = 15) older women underwent body composition analysis via dual-energy X-ray absorptiometry (DXA) and performed the following measures: bench press (BP) 1-repetition maximum strength (1RM), vertical jump height and power, handgrip strength, Timed Up and Go test, Berg Balance Scale testing, and bench press power testing at 20%, 40%, and 60% 1RM.
Regression analyses revealed 3 significant models accounting for 93.8%, 91.1%, and 86.4% of the variance in DXA-derived ASM. Paired-samples t tests revealed no significant differences between model-derived and DXA-derived ASM for each model, and each model was significantly correlated to DXA-derived ASM (P < .001). In addition, each model revealed a strong ability to appropriately classify sarcopenia status, with the area under the curve values ranging from 0.86 to 0.93. The present data indicate that ASM can be determined with high precision by measuring outcome variables such as jump power, body weight, and grip strength in older women.
Therefore, the present models could be used to identify, screen, or classify older women as sarcopenic, ultimately allowing the implementation of interventions aimed at decreasing the difficulty of activities of daily living and increasing quality of life.
既往文献表明,与去脂体重相比,四肢骨骼肌质量(ASM)的减少对肌少症的发生和进展可能具有更大的不利影响。不幸的是,由于获得准确测量 ASM 的设备受限,许多人未被诊断出患有肌少症,并经历了功能下降。因此,本研究旨在确定功能和神经肌肉测量在识别老年女性 ASM 中的能力。
41 名(肌少症 n = 15)老年女性接受了双能 X 射线吸收法(DXA)的身体成分分析,并进行了以下测量:卧推 1 次重复最大力量(1RM)、垂直跳跃高度和力量、握力、计时起立行走测试、伯格平衡量表测试以及在 20%、40%和 60% 1RM 下的卧推功率测试。
回归分析显示,有 3 个显著模型可解释 DXA 测量的 ASM 方差的 93.8%、91.1%和 86.4%。配对样本 t 检验显示,每个模型的模型推导的 ASM 与 DXA 推导的 ASM 之间没有显著差异,并且每个模型都与 DXA 推导的 ASM 显著相关(P <.001)。此外,每个模型都显示出适当分类肌少症状态的强大能力,曲线下面积值范围为 0.86 至 0.93。本数据表明,通过测量老年女性的跳跃力量、体重和握力等结果变量,可以高精度地确定 ASM。
因此,目前的模型可以用于识别、筛选或分类老年女性为肌少症患者,最终可以实施旨在降低日常生活活动难度和提高生活质量的干预措施。