Belhassine Maia, Papakrivopoulou Eugenia, Venet Christian, Mestdagh Carole, Schroeven Marc
Department of Pulmonary Medicine, Clinique Saint Jean, Brussels, Belgium.
Department of Internal Medicine and Nephrology, Clinique Saint Jean, Brussels, Belgium.
J Gastrointest Oncol. 2018 Dec;9(6):1207-1212. doi: 10.21037/jgo.2018.07.06.
Pulmonary lymphangitic carcinomatosis (PLC) is a well-known form of tumour metastasis to the pulmonary lymphatic system or to the adjacent interstitial tissue resulting in thickening of the bronchovascular bundle and septa. Another type of tumour metastasis to the lung involves the pulmonary vascular system and is known as pulmonary tumour thrombotic microangiopathy (PTTM). In this article, we will describe the unusual case of a young Chinese woman with gastric adenocarcinoma revealed by atypical radiographic lesions consistent with both PLC and PTTM. We will discuss the existing evidence and hypotheses about the pathophysiology of both conditions.
肺淋巴管癌病(PLC)是一种众所周知的肿瘤转移形式,可转移至肺淋巴系统或相邻的间质组织,导致支气管血管束和小叶间隔增厚。另一种肿瘤转移至肺部的类型涉及肺血管系统,称为肺肿瘤血栓性微血管病(PTTM)。在本文中,我们将描述一名年轻中国女性的罕见病例,其胃腺癌通过与PLC和PTTM均相符的非典型影像学病变得以揭示。我们将讨论关于这两种病症病理生理学的现有证据和假说。