Assao Agnes, de Souza Talita-da Silva-Nery, Freitas Diogo-Loureiro, Oliveira Denise-Tostes
DDS, MSc, PhD Student, Department of Surgery, Stomatology, Pathology and Radiology, Area of Pathology, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
DDS, Department of Surgery, Stomatology, Pathology and Radiology, Area of Pathology, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
J Clin Exp Dent. 2018 Nov 1;10(11):e1135-e1139. doi: 10.4317/jced.55088. eCollection 2018 Nov.
The intraosseous mucoepidermoid carcinoma is a rare lesion that frequently affects the posterior region of the mandible. This case reports a multilocular osteolytic radiolucency with two years of evolution, that expanded and perforated the cortical bone, with irregular and indefinite margins, that extended from the mandibular angle to the ascendant ramus, with cutaneous ulceration, detected in a 51 years-old male. An incisional biopsy was performed and confirmed the diagnosis of low-grade intraosseous mucoepidermoid carcinoma. The patient was submitted to partial mandibulectomy, neck dissection and post-operative radiotherapy. In three years of follow-up, there was no evidence of tumor recurrence. This case report reinforces that even a low-grade intraosseous mandibular mucoepidermoid carcinoma tends to expand and to perforate the bone cortical, infiltrating to adjacent soft tissues, in long time of evolution. Intraosseous, mucoepidermoid carcinoma, mandible.
骨内黏液表皮样癌是一种罕见病变,常累及下颌骨后部区域。本病例报告了一名51岁男性患者,其病变为多房性骨质溶解性透射区,病程两年,病变扩展并穿破皮质骨,边界不规则且不明确,从下颌角延伸至升支,伴有皮肤溃疡。进行了切开活检,确诊为低级别骨内黏液表皮样癌。患者接受了下颌骨部分切除术、颈部清扫术及术后放疗。随访三年,无肿瘤复发迹象。本病例报告强调,即使是低级别骨内下颌黏液表皮样癌,在病程较长时也倾向于扩展并穿破骨皮质,浸润至相邻软组织。骨内、黏液表皮样癌、下颌骨。