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纳米技术在糖尿病管理中的作用。

Role of Nanotechnology in Diabetic Management.

机构信息

Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak-124001, India.

Shri Baba Mastnath Institute of Pharmaceutical Sciences and Research, Baba Mastnath University, Rohtak-124001, India.

出版信息

Recent Pat Nanotechnol. 2019;13(1):28-37. doi: 10.2174/1872210513666190104122032.

Abstract

BACKGROUND

Diabetes Mellitus (DM) has emerged as an epidemic that has affected millions of people worldwide in the last few decades. Nanotechnology is a discipline that is concerned with material characteristics at nanoscale and offers novel techniques for disease detection, management and prevention.

OBJECTIVE

Diabetes mellitus is an epidemic disease that has affected millions of people globally. Nanotechnology has greatly enhanced the health status by providing non-obtrusive techniques for the management and treatment of diabetic patients.

METHOD

In diabetes research, the nanotechnology has encouraged the advancement of novel glucose monitoring and several modalities for insulin delivery holding possibilities to enhance the personal satisfaction and life quality for diabetic patients.

RESULT

Nanoparticles hold a great potential in the areas of drug delivery and are explored as vehicles for orally administered insulin formulations. Glucose biosensors equipped with nanoscale materials such as Quantum Dots (QDs), Carbon Nanotubes (CNTs), Magnetic Nanoparticles (MNPs) etc. have shown greater sensitivity. Nanotechnology in diabetic research is heading towards the novel techniques which can provide continuous glucose monitoring offering accurate information and improving patient's compliance.

CONCLUSION

The present review addresses the different aspects of nanoparticles and recent patents related to diabetic management based on nanotechnology.

摘要

背景

在过去几十年中,糖尿病(DM)已成为一种在全球范围内影响数百万人的流行病。纳米技术是一门关注纳米尺度材料特性的学科,为疾病的检测、管理和预防提供了新的技术。

目的

糖尿病是一种全球性的流行病,影响了数百万人。纳米技术通过为糖尿病患者的管理和治疗提供非侵入性技术,极大地提高了健康水平。

方法

在糖尿病研究中,纳米技术鼓励了新型葡萄糖监测和几种胰岛素输送方式的发展,有可能提高糖尿病患者的个人满意度和生活质量。

结果

纳米颗粒在药物输送领域具有巨大的潜力,被探索作为口服胰岛素制剂的载体。配备纳米级材料(如量子点(QDs)、碳纳米管(CNTs)、磁性纳米颗粒(MNPs)等)的葡萄糖生物传感器显示出更高的灵敏度。糖尿病研究中的纳米技术正在朝着能够提供连续葡萄糖监测的新技术发展,提供准确的信息并提高患者的依从性。

结论

本综述讨论了纳米颗粒的不同方面以及基于纳米技术的糖尿病管理的最新专利。

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