Department of Neurology, Sunshine Hospital, Western Health, St Albans, Victoria, Australia,
Department of Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, Australia,
Neuroepidemiology. 2019;52(1-2):104-110. doi: 10.1159/000494758. Epub 2019 Jan 9.
Migraine is one of the most prevalent neurological disorders among all age groups including the elderly, but the incidence and prevalence of migraine tend to decrease with age. The clinical phenotype of migraine also appears to be different in the elderly patient group in comparison to the younger patient group, with elderly migraine appearing to be more often bilateral and associated with what has become known as "late-life migraine accompaniments. Furthermore, difficulty in the differentiation of migraine from vascular insults such as transient ischemic attacks and amyloid angiopathy and other multiple comorbidities, polypharmacy and age-related changes in pharmacodynamics and pharmacokinetics makes treatments for this cohort challenging but necessary, especially given the worldwide increase in life expectancy, and likelihood of migraine continuing to be a major personal and public health problem.
偏头痛是一种最常见的神经疾病在所有年龄段包括老年人, 但偏头痛的发病率和患病率往往随着年龄的增长而下降。偏头痛的临床表型也似乎不同在老年患者组与年轻的患者组, 老年偏头痛似乎更常见的双侧和相关联的所谓“晚年偏头痛伴随。此外, 偏头痛从血管损伤如短暂性脑缺血发作和淀粉样血管病和其他多种合并症的鉴别困难, 多药和年龄相关的药效学和药代动力学变化使得这个队列的治疗具有挑战性但也是必要的, 特别是考虑到全球预期寿命的增加, 以及偏头痛继续成为一个主要的个人和公共卫生问题的可能性。