Kline M W, Kaplan S L
Department of Pediatrics, St. Louis University School of Medicine, MO 63104.
Pediatr Infect Dis J. 1988 Dec;7(12):855-7.
The hospital records of 85 children with bacterial meningitis were reviewed and a subset of 25 children who underwent computed tomography of the head were identified. The major stated indications for computed tomography were fever (8 patients), seizures (4 patients), signs of increased intracranial pressure (4 patients), focal neurologic dysfunction (3 patients) and recurrent meningitis (2 patients). Abnormal findings were demonstrated by computed tomography in 20 of 25 patients but in 8 patients consisted solely of nonspecific dilatation of spaces containing cerebrospinal fluid or of basilar enhancement. The yield of information that was useful either diagnostically or therapeutically was low; positive findings of obvious clinical relevance were present in only 2 cases. Computed tomography provides an accurate means of diagnosing intracranial complications of bacterial meningitis. It must be used conservatively, however, to limit expense and radiation exposure and enhance the yield of potentially relevant information. Computed tomography is indicated for children with persistent neurologic dysfunction, persistently positive cerebrospinal fluid cultures or recurrent meningitis, whereas it is of little value for children with prolonged fever alone.
回顾了85例细菌性脑膜炎患儿的医院记录,并确定了其中25例行头部计算机断层扫描的患儿亚组。计算机断层扫描的主要既定指征为发热(8例)、癫痫发作(4例)、颅内压升高体征(4例)、局灶性神经功能障碍(3例)和复发性脑膜炎(2例)。25例患者中有20例计算机断层扫描显示异常结果,但其中8例仅表现为含脑脊液间隙的非特异性扩张或基底强化。无论是诊断还是治疗方面,有用信息的获取率都很低;仅有2例出现具有明显临床相关性的阳性结果。计算机断层扫描是诊断细菌性脑膜炎颅内并发症的准确方法。然而,必须谨慎使用,以限制费用和辐射暴露,并提高潜在相关信息的获取率。对于有持续性神经功能障碍、脑脊液培养持续阳性或复发性脑膜炎的患儿,建议进行计算机断层扫描,而对于仅长期发热的患儿,其价值不大。