Zhu Fang, Zhang Baixue, Zhu Wenhui
Department of Ultrasonography, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Department of Ultrasonography, Zhuhai People's Hospital, Zhuhai Guangdong 519001, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Dec 28;43(12):1309-1314. doi: 10.11817/j.issn.1672-7347.2018.12.005.
To evaluate the volume and function of left atrium and left atrial appendage in patients with atrial fibrillation by three-dimensional transesophageal echocardiography and transthoracic echocardiography. Methods: A total of 112 patients with atrial fibrillation were divided into two groups: a paroxysmal atrial fibrillation (ParAF) group (n=80) and a persistent atrial fibrillation (PerAF) group (n=32). Control group was people without atrial fibrillation (n=40). Clinical data of the participants were collected. Left atrial dimension (LAD), left atrial volume (LAV), left ventricular end-diastolic volume (LVEDV) and left ventricular end-systolic volume (LVESV) were measured by transthoracic echocardiography, while left atrial appendage peak emptying flow velocity (LAAeV), left atrial appendage peak filling flow velocity (LAAfV), left atrial appendage maximum volume (LAAVmax) and left atrial appendage minimum volume (LAAVmin) were measured by three-dimensional transesophageal echocardiography. Left atrial volume index (LAVI), left ventricular ejection fraction (LVEF) and left atrial appendage ejection fraction (LAAEF) were calculated. Results: Compared with the control group, LAAEF, LAAeV and LAAfV in the ParAF group were decreased obviously, while LAD, LAV, LAVI, LAAVmax and LAAVmin in the ParAF group were increased obviously (P<0.05). Compared with the ParAF group, LAAEF, LAAeV and LAAfV in the PerAF group were also decreased obviously, and LAD, LAV, LAVI, LAAVmax and LAAVmin in the ParAF group were also increased obviously (P<0.05). There was no statistically significant difference in LVEDV, LVESV, LVEF between the ParAF group and the PerAF group (P<0.05). Conclusion: Left atrium and left atrial appendage were enlarged and the function of left atrial appendage was declined in patients with AF, and the changes were more obvious in patients with PerAF compared with patients with ParAF by three-dimensional transesophageal echocardiography and transthoracic echocardiography.
通过三维经食管超声心动图和经胸超声心动图评估心房颤动患者左心房及左心耳的容积和功能。方法：将112例心房颤动患者分为两组：阵发性心房颤动（ParAF）组（n = 80）和持续性心房颤动（PerAF）组（n = 32）。对照组为无房颤的人群（n = 40）。收集参与者的临床资料。经胸超声心动图测量左心房内径（LAD）、左心房容积（LAV）、左心室舒张末期容积（LVEDV）和左心室收缩末期容积（LVESV），三维经食管超声心动图测量左心耳峰值排空流速（LAAeV）、左心耳峰值充盈流速（LAAfV）、左心耳最大容积（LAAVmax）和左心耳最小容积（LAAVmin）。计算左心房容积指数（LAVI）、左心室射血分数（LVEF）和左心耳射血分数（LAAEF）。结果：与对照组相比，ParAF组的LAAEF、LAAeV和LAAfV明显降低，而ParAF组的LAD、LAV、LAVI、LAAVmax和LAAVmin明显增加（P < 0.05）。与ParAF组相比，PerAF组的LAAEF、LAAeV和LAAfV也明显降低，ParAF组的LAD、LAV、LAVI、LAAVmax和LAAVmin也明显增加（P < 0.05）。ParAF组和PerAF组之间的LVEDV、LVESV、LVEF差异无统计学意义（P < 0.05）。结论：通过三维经食管超声心动图和经胸超声心动图评估，房颤患者左心房和左心耳增大，左心耳功能下降，与阵发性房颤患者相比，持续性房颤患者的变化更明显。
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