Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System.
Health Psychol. 2019 Feb;38(2):113-121. doi: 10.1037/hea0000706.
This study examined the impact of early life trauma (ELT) on cardio-metabolic health in veterans from post-9/11 conflicts who experience significant stress from deployment and reintegration.
Three hundred thirty-seven veterans from the Translational Research Center for Traumatic Brain Injury and Stress Disorders study underwent physiological assessments, including blood pressure and waist circumference. Fasting blood samples were collected to measure metabolic syndrome (MetS; cholesterol/triglycerides/glucose). ELT history was determined using the Traumatic Life Events Questionnaire. Posttraumatic stress disorder (PTSD) symptoms were assessed using the Clinician-Administered PTSD Scale. Logistic regression models examined the association of ELT and MetS diagnostic criteria while controlling for confounders.
The adjusted logistic regression showed a significant relationship between interpersonal ELT (IP ELT) and risk of MetS, with IP ELT having an approximately 3-fold increase in the risk of cardio- metabolic syndrome compared with those with no trauma (odds ratio [OR] = 3.06, p < .05). IP ELT was associated with over a 2-fold increased risk of elevated triglycerides compared with those with no trauma (OR = 2.06, p < .05). PTSD symptoms also explained in part the IP-ELT/MetS relationship. Veterans with any ELT were significantly more likely to meet for a current diagnosis of PTSD.
Our findings suggest that veterans with IP ELT are more likely to meet MetS and PTSD diagnostic criteria than veterans without IP ELT. This is concerning considering the young age of the sample and stresses the importance of an integrated and holistic approach in the assessment of physical and mental health in returning veterans. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
本研究考察了经历过部署和再融入带来的巨大压力的后 9/11 冲突退伍军人的早期生活创伤(ELT)对心脏代谢健康的影响。
337 名来自创伤性脑损伤和应激障碍转化研究中心的退伍军人接受了生理评估,包括血压和腰围。采集空腹血样以测量代谢综合征(MetS;胆固醇/甘油三酯/葡萄糖)。使用创伤生活事件问卷确定 ELT 病史。使用临床医生管理的创伤后应激障碍量表评估 PTSD 症状。逻辑回归模型检查了 ELT 与 MetS 诊断标准之间的关联,同时控制了混杂因素。
调整后的逻辑回归显示,人际 ELT(IP ELT)与 MetS 风险之间存在显著关系,与无创伤者相比,IP ELT 患心脏代谢综合征的风险增加了约 3 倍(优势比 [OR] = 3.06,p <.05)。与无创伤者相比,IP ELT 与甘油三酯升高的风险增加了两倍以上(OR = 2.06,p <.05)。PTSD 症状也部分解释了 IP-ELT/MetS 之间的关系。有任何 ELT 的退伍军人更有可能被诊断为 PTSD。
我们的研究结果表明,与无 IP ELT 的退伍军人相比,有 IP ELT 的退伍军人更有可能符合 MetS 和 PTSD 的诊断标准。考虑到样本的年龄较轻,这令人担忧,这强调了在评估返回的退伍军人的身心健康时采用综合和整体方法的重要性。