Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA; The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, NH, USA.
Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA; The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, NH, USA.
J Shoulder Elbow Surg. 2019 Apr;28(4):765-773. doi: 10.1016/j.jse.2018.10.004. Epub 2019 Jan 15.
Recent literature has shown that acute reverse total shoulder arthroplasty (RTSA) yields good outcomes in the treatment of displaced proximal humeral fractures, and there have also been recent studies showing that delayed RTSA can be successfully used for sequelae of proximal humeral fractures such as nonunion and malunion. The use of meta-analysis affords the opportunity to formally compare the outcomes of acute RTSA for fracture and delayed RTSA for fracture sequelae.
We searched the MEDLINE, Embase, and Cochrane Library databases. We included all studies reporting on RTSA for the treatment of proximal humeral fracture sequelae with a comparison group of acute RTSA or with no comparison group in adults with a mean age older than 65 years and at least 2 years of follow-up. We calculated weighted mean differences for range of motion, standardized mean differences for clinical outcome scores, and relative risks for dichotomous outcomes.
Sixteen studies met the inclusion criteria, which comprised 322 patients undergoing RTSA for fracture sequelae. Of these studies, 4 were comparative (46 patients) whereas 12 were case series (276 patients). Among studies directly comparing acute versus delayed RTSA, no differences in forward flexion (P = .72), clinical outcome scores (P = .78), or all-cause reoperation (P = .92) were found between the 2 groups. Patients undergoing delayed RTSA achieved 6° more external rotation than those undergoing acute RTSA; this difference was significant (P = .01).
Given the risks associated with surgery in the elderly population, consideration may be given to an initial trial of nonoperative treatment in these patients, saving RTSA for those in whom nonoperative treatment fails without compromising the ultimate outcome.
近期文献表明,急性反式全肩关节置换术(RTSA)治疗移位肱骨近端骨折效果良好,且近期亦有研究表明,延迟 RTSA 可成功用于肱骨近端骨折的后遗症,如骨折不愈合和畸形愈合。荟萃分析提供了正式比较急性 RTSA 治疗骨折和延迟 RTSA 治疗骨折后遗症的机会。
我们检索了 MEDLINE、Embase 和 Cochrane 图书馆数据库。我们纳入了所有报告 RTSA 治疗肱骨近端骨折后遗症的研究,其比较组为急性 RTSA 或在年龄大于 65 岁且随访至少 2 年的成人中无比较组。我们计算了运动范围的加权均数差、临床结局评分的标准化均数差以及二分类结局的相对风险。
16 项研究符合纳入标准,共 322 例患者接受 RTSA 治疗骨折后遗症。其中,4 项研究为比较性研究(46 例患者),12 项研究为病例系列研究(276 例患者)。在直接比较急性与延迟 RTSA 的研究中,两组间前屈(P = .72)、临床结局评分(P = .78)或所有原因再手术(P = .92)均无差异。行延迟 RTSA 的患者外旋角度比行急性 RTSA 的患者多 6°;这一差异具有统计学意义(P = .01)。
鉴于老年人群手术相关风险,可考虑对这些患者进行初始非手术治疗尝试,将 RTSA 保留给那些非手术治疗失败但不影响最终结局的患者。