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心房颤动:沙特阿拉伯吉达一家三级医疗中心的风险因素及合并症

Atrial fibrillation: risk factors and comorbidities in a tertiary center in Jeddah, Saudi Arabia.

作者信息

Mashat Abdullah Abdulfattah, Subki Ahmed Hussein, Bakhaider Moaz Abdulrahman, Baabdullah Wejdan Mohammad, Walid Jawaher Badr, Alobudi Abdulrahman Hatim, Fakeeh Maged Mazen, Algethmi Anas Jamal, Alhejily Wesam Awad

机构信息

Department of Internal Medicine, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia,

出版信息

Int J Gen Med. 2019 Jan 11;12:71-77. doi: 10.2147/IJGM.S188524. eCollection 2019.

Abstract

INTRODUCTION

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia worldwide and carries significant risk of morbidity and mortality. The prevalence of AF is high in significant parts of the world, but not much is known from countries, such as Saudi Arabia.

AIMS

To study the risk factors, etiologies, comorbidities, and outcome of AF in Saudi Arabia.

PATIENTS AND METHODS

A retrospective study was conducted in King Abdul-Aziz Hospital in Jeddah during the period 2010-2017. Data were collected from both the electronic-and paper-based medical records of patients with AF. The data included the demographic information, adverse lifestyle (smoking and obesity), cardiothoracic surgery, and comorbidities.

RESULTS

A total of 167 patients were included in the analysis (43% were males). The mean age was 63.3±35 years and the mean body mass index was 28.8±83. Hypertension (HTN) was the most prevalent risk factor encountered (73.1%). This was followed by valvular heart disease, and type 2 diabetes mellitus (T2DM), which occurred in 58.7% and 53.3% of patients, respectively. Valvular heart disease was significantly associated with older age (=0.002) and coronary artery disease (CAD) (=0.001). Heart failure (HF) was associated with HTN (=0.005), coronary heart disease (=0.001), and chronic kidney disease (CKD) (=0.003).

CONCLUSION

AF was more prevalent among females in Saudi Arabia. HTN, valvular heart disease, and T2DM were the most prevalent risk factors of AF in Saudi Arabia. Valvular heart disease was more prevalent among older patients and significantly associated with CAD. HTN, CAD, and CKD were the most significant risk factors for HF in patients with AF.

摘要

引言

心房颤动(AF)是全球最常见的心律失常类型,具有较高的发病和死亡风险。世界上许多地区AF的患病率都很高,但沙特阿拉伯等国家的相关情况知之甚少。

目的

研究沙特阿拉伯AF的危险因素、病因、合并症及预后。

患者与方法

2010年至2017年期间在吉达的阿卜杜勒-阿齐兹国王医院进行了一项回顾性研究。从AF患者的电子和纸质病历中收集数据。数据包括人口统计学信息、不良生活方式(吸烟和肥胖)、心胸外科手术及合并症。

结果

共有167例患者纳入分析(43%为男性)。平均年龄为63.3±35岁,平均体重指数为28.8±83。高血压(HTN)是最常见的危险因素(73.1%)。其次是瓣膜性心脏病和2型糖尿病(T2DM),分别发生在58.7%和53.3%的患者中。瓣膜性心脏病与高龄(=0.002)和冠状动脉疾病(CAD)(=0.001)显著相关。心力衰竭(HF)与HTN(=0.005)、冠心病(=0.001)和慢性肾脏病(CKD)(=0.003)相关。

结论

AF在沙特阿拉伯女性中更为普遍。HTN、瓣膜性心脏病和T2DM是沙特阿拉伯AF最常见的危险因素。瓣膜性心脏病在老年患者中更为普遍,且与CAD显著相关。HTN、CAD和CKD是AF患者发生HF的最重要危险因素。

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