Dubinskaya Ekaterina D, Gasparov Alexandr S, Babichevа Irina A, Kolesnikova Svetlana N
Obstetrics and Gynecology Department with Perinatology Course of Medical Institute, RUDN University, 117198, 8 Miklukho-Maklay Str., Moscow, Russian Federation.
Department of Obstetrics, Gynecology and Reproductive Medicine, RUDN University, 117198, 8 Miklukho-Maklay Str., Moscow, Russian Federation.
Eur J Obstet Gynecol Reprod Biol. 2019 Mar;234:120-125. doi: 10.1016/j.ejogrb.2019.01.017. Epub 2019 Jan 18.
The purpose of study is to evaluate the recurrence rate of pelvic organ prolapse after surgical treatment and pre- to postoperative changes in sexual function of patients with different stages of pelvic organ prolapse.
The presented study was a single-centre observational nonrandomized analysis of an ongoing prospective cohort study evaluating anatomical and clinical outcomes in reproductive aged women scheduled for nature tissue repair of POP staged I-III. Two hundred and ten women were recruited, of whom 120 (57.1%) had the advanced prolapse form (POP-Q III). Women at preoperative POP stage I-II were compared with women at stage III without apical prolapse.
The best effectively rate with low recurrence depends on preoperative prolapse stage. The overall objective success rate was about 80% in five years in patients with preoperative stage I-II. Study shows a significant improvement in sexual function in all patients with pelvic organ prolapse in five years after surgery.
This study showed that women with advanced POP have a higher risk of recurrence after POP native tissue repair compared with early stages and proved the improvement of sexual function especially in women with advanced prolapse forms. Women with early stage of POP should be advised to postpone surgery until progression of complaints because of the high recurrence risk.
本研究旨在评估盆腔器官脱垂手术治疗后的复发率以及不同阶段盆腔器官脱垂患者术前至术后性功能的变化。
本研究是一项单中心观察性非随机分析,来自一项正在进行的前瞻性队列研究,该队列研究评估计划进行Ⅰ-Ⅲ期盆腔器官脱垂自然组织修复的育龄妇女的解剖学和临床结局。共招募了210名妇女,其中120名(57.1%)患有晚期脱垂形式(盆腔器官脱垂定量分期系统Ⅲ期)。将术前盆腔器官脱垂Ⅰ-Ⅱ期的妇女与无顶端脱垂的Ⅲ期妇女进行比较。
低复发率的最佳有效率取决于术前脱垂阶段。术前Ⅰ-Ⅱ期患者五年的总体客观成功率约为80%。研究表明,所有盆腔器官脱垂患者术后五年性功能均有显著改善。
本研究表明,与早期相比,晚期盆腔器官脱垂妇女在盆腔器官脱垂自然组织修复后复发风险更高,并证明性功能有所改善,尤其是晚期脱垂形式的妇女。由于复发风险高,建议早期盆腔器官脱垂妇女推迟手术,直到症状进展。