a Department of Neuroradiology and Endovascular Treatment , Jean-Minjoz University Hospital , Besancon , France.
b Department of Interventional Neuroradiology , Erasmus University Hospital , Brussels , Belgium.
Expert Rev Med Devices. 2019 Mar;16(3):237-251. doi: 10.1080/17434440.2019.1575725. Epub 2019 Feb 6.
Intracranial aneurysms in distal locations are sometimes difficult to treat due to their branching locations and the presence of blister-like or very wide-necked aneurysms. Braided intracranial stents, including flow diverters (FDs) and low-profile braided intracranial stents (LPBSs) may provide additional advantages, due to their flow-diverting properties.
The use of FDs in off-label, distal intracranial locations has been increasing with promising outcomes and has given rise to the LPBS, which has less flow-diverting properties, allowing for easier use in distal branching sites through 0.017' microcatheters. These devices have shifted the interest from the aneurysm's sac filling to the regional remodeling through the effect of flow diversion. The purpose of this article is to discuss their functionality, safety, performance, and perspectives through a critical review of important publications of the last 11.5 years (January 2007 to July 2018) on the use of these devices at and beyond the circle of Willis.
FDs modify the regional anatomy thus careful pre-procedural consideration of the regional hemodynamic equilibrium is mandatory, as well as effective antiplatelet regimen. LPBSs provide moderate flow-diversion effect, which may be an advantage, especially for very distal and small aneurysms.
由于分支位置和疱状或非常宽颈动脉瘤的存在,远端部位的颅内动脉瘤有时难以治疗。编织颅内支架,包括血流导向装置(FD)和低剖面编织颅内支架(LPBS),由于其血流转向特性,可能具有额外的优势。
FD 在颅内远端的非适应证部位的使用越来越多,其结果令人鼓舞,并催生了 LPBS,它的血流转向特性较低,通过 0.017'微导管更容易用于远端分支部位。这些设备通过血流转向的作用,将人们的兴趣从动脉瘤囊的填充转移到区域性重塑上。本文通过对过去 11.5 年(2007 年 1 月至 2018 年 7 月)重要出版物的批判性回顾,讨论了这些装置在 Willis 环内外的功能、安全性、性能和前景,这些出版物涉及这些装置在颅内远端和 Willis 环以外部位的使用。
FD 改变了区域性解剖结构,因此必须在术前仔细考虑区域性血流动力学平衡,并采用有效的抗血小板治疗方案。LPBS 提供适度的血流转向效果,这可能是一个优势,特别是对于非常远端和小的动脉瘤。