Ramkumar Subramaniam
Consultant in Pathology, Neuberg Anand Reference Laboratories, Neuberg Diagnostics Pvt. Ltd., Thombra Arcade, Elamakkara Road, Kaloor, Cochin-682017, India.
Case Rep Pathol. 2018 Dec 26;2018:4847286. doi: 10.1155/2018/4847286. eCollection 2018.
We present a case of sequestrated meningocele in a 1-year-old girl, who presented with a 1x1cm occipital swelling since birth. CT brain revealed the soft tissue swelling to be extracranial. She underwent surgical excision of the specimen and the excised mass was sent for histopathological examination. The specimen consisted of skin and subcutaneous tissue measuring 2 x 1 x 1 cm. The entire tissue was paraffin processed. Multiple sections studied from the lesion showed an ill circumscribed locally infiltrative dermal lesion. The lesion was composed of whorled proliferations of meningothelial cells enclosing pseudovascular spaces. Immunohistochemically the lesion was positive for EMA, Desmin, and negative for endothelial markers. The present case was documented as a rare case of a rudimentary meningocele.
我们报告一例1岁女童的隐匿性脑脊膜膨出病例,该女童自出生以来枕部有一个1×1厘米的肿胀。脑部CT显示软组织肿胀位于颅外。她接受了标本的手术切除,并将切除的肿块送去做组织病理学检查。标本由皮肤和皮下组织组成,大小为2×1×1厘米。整个组织进行了石蜡处理。对病变部位进行的多个切片研究显示,有一个边界不清、局部浸润性的真皮病变。该病变由围绕假血管腔隙的脑膜内皮细胞呈涡状增生构成。免疫组化显示,该病变对上皮膜抗原(EMA)、结蛋白呈阳性,对内皮标志物呈阴性。本病例被记录为罕见的原始脑脊膜膨出病例。