奥司他韦致库欣病患者中毒性表皮坏死松解症。
Oseltamivir-induced toxic epidermal necrolysis in a patient with Cushing's disease.
机构信息
Department of Dermatology, La Paz University Hospital, Autonomous University of Madrid; PIELenRed Consortium, Príncipe de Asturias University Hospital, Alcalá de Henares, Madrid, Spain.
Department of Endocrinology and Nutrition, University Hospital Complex of Albacete, Albacete, Spain.
出版信息
Indian J Dermatol Venereol Leprol. 2020 Sep-Oct;86(5):515-518. doi: 10.4103/ijdvl.IJDVL_53_18.
We report a case of a patient with Cushing's disease with oseltamivir-induced toxic epidermal necrolysis, who was treated with cyclosporine with favorable evolution. There is only one case reported of Cushing's disease and toxic epidermal necrolysis and very few oseltamivir-induced toxic epidermal necrolysis cases in literature. This report also discusses the role that the preexisting hypercortisolism condition may have played in the development and favorable resolution of the toxic epidermal necrolysis.
我们报告了一例库欣病伴奥司他韦诱导的中毒性表皮坏死松解症患者，该患者接受环孢素治疗后病情好转。文献中仅报道过一例库欣病和中毒性表皮坏死松解症，以及极少数奥司他韦诱导的中毒性表皮坏死松解症病例。本报告还讨论了先前存在的皮质醇增多症状态在中毒性表皮坏死松解症的发生和良好缓解中可能发挥的作用。
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