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孕期应在何时进行衣原体筛查?

[When in pregnancy should screening for Chlamydia be carried out?].

作者信息

Schlögl H, Rudelstorfer R, Kosian K

机构信息

II. Universitäts-Frauenklinik Wien.

出版信息

Z Geburtshilfe Perinatol. 1988 Nov-Dec;192(6):263-5.

PMID:3068932
Abstract

One goal of every prenatal care should be the diagnosis of a cervical infection with Chlamydia trachomatis and the prevention of its transmission to the neonate. Therefore, we studied the questions (1) at which gestational age a screening would be most meaningful and (2) whether the woman's medical history, a vaginal smear or cervical cerclage suggests any risk of infection. 11 of 121 pregnant women (9.1%) had a positive test for cervical infection with Chlamydia trachomatis at their booking visit. More than half of them had a spontaneous remission at the follow-up visit. Practically, all newborns to infected mothers (at follow-up visits) had a positive test as well. We did not find any relationship between the medical history, vaginal smear or cervical cerclage and the incidence of Chlamydia trachomatis infection. In conclusion, we propose a screening for Chlamydia trachomatis infection of all pregnant women between the 34th and 38th week of gestation and treatment of infected individuals with erythromycin (4 x 500 mg t.i.d.).

摘要

每次产前检查的一个目标应该是诊断沙眼衣原体宫颈感染并防止其传播给新生儿。因此,我们研究了以下问题:(1)在哪个孕周进行筛查最有意义;(2)女性的病史、阴道涂片或宫颈环扎术是否提示任何感染风险。121名孕妇中有11名(9.1%)在初次就诊时沙眼衣原体宫颈感染检测呈阳性。其中一半以上在随访时自然缓解。实际上,所有感染母亲的新生儿(在随访时)检测也呈阳性。我们未发现病史、阴道涂片或宫颈环扎术与沙眼衣原体感染发生率之间存在任何关联。总之,我们建议对妊娠34至38周的所有孕妇进行沙眼衣原体感染筛查,并用红霉素(4×500毫克,每日三次)治疗感染者。

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