[创伤后癫痫：一项前瞻性队列研究]
[Posttraumatic seizures: a prospective cohort study].
作者信息
Krylov V V, Teplyshova A M, Mutaeva R S, Yakovlev A A, Kaimovsky I L, Asratyan S A, Sinkin M V, Kordonskaya O O, Trifonov I S, Guekht A B
机构信息
Evdokimov Moscow State University of Medical Dentistry, Moscow, Russia; Sklifosovsky Research Institute of Emergenscy Medicine, Moscow, Russia; Clinical Medical Centre of Evdokimov Moscow State University of Medical Dentisity, Moscow, Russia.
Moscow Research and Clinical Center for Neuropsychiatry of the Healthcare Department, Moscow, Russia.
出版信息
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(10. Vyp. 2):3-8. doi: 10.17116/jnevro20181181023.
AIM
To evaluate the incidence and risk factors for posttraumatic seizures (PTS).
MATERIAL AND METHODS
The authors conducted a prospective study of 237 patients with TBI of varying severity. The patients were hospitalized and examined in Moscow neurosurgery departments. Then they participated in the follow-up observation for 2 years. PTS were classified as early (occurred from 1 to 7 days after TBI) and late (occurred later than 7 days).
RESULTS AND CONCLUSION
Forty-three people (18.1%) experienced early seizures, 15 patients (6.3%) had late seizures. The early seizures were the significant predictor of the late seizures. In the group of patients with early seizures, the proportion of severe TBI was significantly higher. Subdural hematoma, depressed skull fracture, alcohol abuse were reliable predictors of early and late PTS. Thus, these factors increased the risk of posttraumatic epilepsy (PTE).
目的
评估创伤后癫痫（PTS）的发病率及危险因素。
材料与方法
作者对237例不同严重程度的创伤性脑损伤（TBI）患者进行了一项前瞻性研究。这些患者在莫斯科神经外科科室住院并接受检查。然后他们参与了为期2年的随访观察。PTS被分为早期（在TBI后1至7天发生）和晚期（在7天后发生）。
结果与结论
43人（18.1%）发生早期癫痫，15例患者（6.3%）发生晚期癫痫。早期癫痫是晚期癫痫的重要预测指标。在早期癫痫患者组中，重度TBI的比例显著更高。硬膜下血肿、颅骨凹陷性骨折、酗酒是早期和晚期PTS的可靠预测指标。因此，这些因素增加了创伤后癫痫（PTE）的风险。
Zotero 插件