波兰宫颈癌的当前管理-对 2002-2014 年问卷调查试验与 ASCO 2016 建议的相关性分析。
Current management of cervical cancer in Poland-Analysis of the questionnaire trial for the years 2002-2014 in relation to ASCO 2016 recommendations.
机构信息
Department of Gynecology and Obstetrics, Jagiellonian University Medical College, Krakow, Poland.
Department of Gynecology and Gynecological Oncology, Faculty of Medicine, Medical University in Bialystok, Bialystok, Poland.
出版信息
PLoS One. 2019 Jan 31;14(1):e0209901. doi: 10.1371/journal.pone.0209901. eCollection 2019.
OBJECTIVES
To assess the survival of patients with cervical cancer (CC). Since the recommendations concerning cervical cancer management adopted by Polish medical societies do not differ significantly from the ESGO or non-European guidelines, and the fact that evaluation of the system for CC treatment in Poland, as well as the mortality rate of Polish women with CC, which is 70% higher than the average for European Union (EU) countries, justifies the hypothesis that treatment of CC in Poland deviates from the Polish and international recommendations. This article puts forward the current management of cervical cancer in Poland and discusses it in the context of ASCO guidelines.
MATERIAL AND METHODS
A survey retrospective multicenter analysis of the medical records of 1247 patients with cervical cancer who underwent treatment for disease and who had completed at least two years of follow-up.
RESULTS
Although concurrent radiotherapy and chemotherapy is a standard treatment of FIGO IB to IVA cervical cancer patients in enhanced- and maximum-resources settings, in our analysis, we found that the percentage of women subjected to chemotherapy was lower than in countries where total survival rates were lower.
CONCLUSION
Within the IA to II A cervical cancer patients studied group, the methods of treatment remained in line with ASCO guidelines for countries with the highest standard of care. Although concurrent radiotherapy and chemotherapy is a standard treatment of FIGO IB to IVA cervical cancer patients in enhanced- and maximum-resources settings, in our analysis, we found that the percentage of women subjected to chemotherapy was lower than in countries where total survival rates were lower. Our findings, together with the inconsistencies within the cervical cancer screening program, may be one of the explanations of poorer survival rate of women with cervical cancer in Poland.
目的
评估宫颈癌（CC）患者的生存率。由于波兰医学协会提出的宫颈癌管理建议与 ESGO 或非欧洲指南并无显著差异，而且波兰 CC 治疗系统的评估以及波兰 CC 女性的死亡率（比欧盟国家的平均水平高 70%）表明波兰的 CC 治疗可能存在与波兰和国际建议不符的情况，因此我们提出了波兰目前的宫颈癌管理方法，并结合 ASCO 指南进行了讨论。
材料和方法
这是一项回顾性多中心调查研究，分析了 1247 例接受宫颈癌治疗且至少完成两年随访的患者的病历。
结果
尽管在资源充足和资源最大化的环境中，同步放化疗是 FIGO IB 至 IVA 期宫颈癌患者的标准治疗方法，但我们的分析发现，接受化疗的女性比例低于总生存率较低的国家。
结论
在研究的 IA 至 IIA 期宫颈癌患者中，治疗方法与 ASCO 指南对于高护理标准的国家一致。尽管在资源充足和资源最大化的环境中，同步放化疗是 FIGO IB 至 IVA 期宫颈癌患者的标准治疗方法，但我们的分析发现，接受化疗的女性比例低于总生存率较低的国家。我们的发现，以及宫颈癌筛查计划中的不一致，可能是波兰宫颈癌女性生存率较差的原因之一。
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