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冠心病患者的传导延迟诱导 J 波增强。

Conduction Delay-Induced J-Wave Augmentation in Patients With Coronary Heart Disease.

机构信息

Cardiovascular Center, Toda Central General Hospital, Toda, Japan; Cooperative Major inAdvance Biomedical Science, Joint Graduate School of Tokyo, Women's Medical University, Waseda University and Tokyo Medical University, Tokyo, Japan.

Cardiovascular Center, Toda Central General Hospital, Toda, Japan; Department of Cardiology, Tokyo Medical University, Tokyo, Japan.

出版信息

Am J Cardiol. 2019 Apr 15;123(8):1262-1266. doi: 10.1016/j.amjcard.2019.01.015. Epub 2019 Jan 24.

DOI:10.1016/j.amjcard.2019.01.015
PMID:30711246
Abstract

Electrocardiogram records were surveyed for the presence of an atrial premature beat (APB) and J waves in patients with coronary heart disease and patients with noncardiac diseases. The prevalence and response of J waves to sudden shortening of the RR interval on the conducted APB were determined and compared between the 2 patients groups. The change in the QRS complexes on the APB was also determined. Among 17,013 patients, 243 patients who underwent percutaneous coronary intervention for acute myocardial infarction or angina pectoris had an APB, and J waves were observed in 16 patients (6.6%). In an additional 729 patients with noncardiac diseases and APB, 19 patients showed J waves (2.6%; p = 0.010). The clinical features were almost similar between the ischemic and nonischemic groups. J waves were located more often in inferior and high lateral leads in the ischemic group. When the RR interval shortened from 942 ± 228 to 621 ± 175 ms and 869 ± 158 to 570 ± 118 ms at baseline and in the conducted APB (p<0.001 for both), the J-wave amplitude increased from 0.16 ± 0.04 to 0.19 ± 0.06 mV (p<0.001) and 0.21 ± 0.07 to 0.24 ± 0.08 mV (p = 0.010) in the ischemic and nonischemic groups, respectively. J waves in patients with chronic coronary heart disease and in patients with noncardiac diseases were augmented at short RR intervals together with distinct changes in the QRS complexes, and an augmentation of J waves at short RR interval may represent a conduction delay.

摘要

对冠心病和非心脏病患者的心电图记录进行了调查,以观察是否存在房性期前收缩(APB)和 J 波。确定了 2 组患者中 J 波对 APB 突然缩短 RR 间期的反应,并进行了比较。还确定了 APB 上 QRS 复合体的变化。在 17013 例患者中,243 例因急性心肌梗死或心绞痛而行经皮冠状动脉介入治疗的患者出现 APB,其中 16 例(6.6%)观察到 J 波。在另外 729 例患有非心脏病和 APB 的患者中,19 例出现 J 波(2.6%;p=0.010)。缺血组和非缺血组的临床特征几乎相似。J 波在下壁导联和高位侧壁导联中更为常见。当 RR 间期从基线时的 942±228ms 缩短至 621±175ms 和从传导性 APB 时的 869±158ms 缩短至 570±118ms 时(p<0.001),J 波幅度从 0.16±0.04mV 增加至 0.19±0.06mV(p<0.001)和从 0.21±0.07mV 增加至 0.24±0.08mV(p=0.010),在缺血组和非缺血组中,分别。慢性冠心病患者和非心脏病患者的 J 波在短 RR 间隔时增强,同时 QRS 复合体发生明显变化,短 RR 间隔时 J 波的增强可能代表传导延迟。

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Contribution of Depolarization and Repolarization Changes to J-Wave Generation and Ventricular Fibrillation in Ischemia.
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Front Physiol. 2020 Sep 30;11:568021. doi: 10.3389/fphys.2020.568021. eCollection 2020.