Goulet O, Revillon Y, Nezelof C, Cerf-Bensussan N, Gallix P, Pellerin D, Ricour C
Département de Pédiatrie, Hôpital des Enfants-Malades, Paris.
Arch Fr Pediatr. 1988;45 Suppl 1:735-9.
A long period of experimental work has allowed to study successively hypothermic preservation of the small bowel, autotransplantation and finally allotransplantation. After this initial phase of experimental surgery, a certain number of intestinal transplantations in humans could be attempted as cyclosporine became available. Following a brief of report of 3 intestinal transplantations recently performed by the group of the hôpital des Enfants-Malades in Paris, indications for intestinal transplantation are provided. Subtotal resections of the small bowel in children or adolescents and extensive resections in neonates account for most of the indications. Despite significant progress, further advances in intestinal transplantation need to be made, because the small bowel poses unique problems in that it seems to represent a compendium of all the particularities and difficulties of other organ transplantations.
经过长期的实验工作，得以相继研究小肠的低温保存、自体移植以及最终的同种异体移植。在经历了实验性外科手术的初始阶段后，随着环孢素的出现，人类的一些肠道移植手术得以尝试。在简要报告了巴黎儿童医院团队最近进行的3例肠道移植手术之后，给出了肠道移植的适应证。儿童或青少年小肠的大部切除以及新生儿的广泛切除是大多数适应证的原因。尽管取得了显著进展，但肠道移植仍需进一步发展，因为小肠存在独特的问题，它似乎汇集了其他器官移植的所有特殊性和困难。
