Division of Plastic Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.
Department of Plastic & Reconstructive Surgery, Johns Hopkins Hospital/University of Maryland Medical Center, Baltimore, Maryland.
Am J Transplant. 2019 Aug;19(8):2284-2293. doi: 10.1111/ajt.15285. Epub 2019 Mar 2.
Panniculectomy can be performed as a prophylactic procedure preceding transplantation to enable obese patients to meet criteria for renal transplantation. No literature exists on combined renal transplant and panniculectomy surgery (LRT-PAN). We describe our 8-year experience performing LRT-PAN. A retrospective chart review of all patients who had undergone LRT-PAN from 2010 to 2018 was conducted. Data were collected on patient demographics, allograft survival and function, and postoperative course. Fifty-eight patients underwent LRT-PAN. All grafts survived, with acceptable function at 1 year. Median length of stay was 4 days with a mean operative duration of 363 minutes. The wound complication rate was 24%. Ninety-day readmission rate was 52%, with medical causes as the most common reason for readmission (45%), followed by wound (32%) and graft-related complications (23%). Body mass index, diabetes status, and previous immunosuppression did not influence wound complication rate or readmission (P = .7720, P = .0818, and P = .4830, respectively). Combining living donor renal transplant and panniculectomy using a multidisciplinary team may improve access to transplantation, particularly for the obese and postobese population. This combined approach yielded shorter-than-expected hospital stays and similar wound complication rates, and thus should be considered for patients in whom transplantation might otherwise be withheld on the basis of obesity.
行预防性的腹带切除术(panniculectomy)可以使肥胖患者符合肾移植标准,从而为其施行肾移植术。目前尚无联合肾移植和腹带切除术(LRT-PAN)的相关文献。我们报告了我们施行该手术的 8 年经验。回顾性分析了 2010 年至 2018 年期间所有接受 LRT-PAN 的患者的病历。收集了患者人口统计学、移植物存活率和功能以及术后病程的数据。58 例患者接受了 LRT-PAN。所有移植物均存活,1 年时功能可接受。中位住院时间为 4 天,平均手术时间为 363 分钟。手术并发症发生率为 24%。90 天再入院率为 52%,再入院的主要原因为医疗原因(45%),其次为伤口(32%)和移植物相关并发症(23%)。BMI、糖尿病状态和既往免疫抑制均未影响伤口并发症发生率或再入院率(P=0.7720,P=0.0818 和 P=0.4830)。使用多学科团队联合施行活体供肾移植和腹带切除术可以增加移植的机会,特别是对于肥胖和超重人群。这种联合方法的住院时间短于预期,且伤口并发症发生率相似,因此对于因肥胖而可能被拒绝接受移植的患者,应考虑这种联合方法。