Northwick Park Hospital, Harrow, UK.
Northwick Park Hospital, Harrow, UK; Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College, London, UK.
Int J Cardiol. 2019 Apr 15;281:107-112. doi: 10.1016/j.ijcard.2019.01.080. Epub 2019 Jan 25.
To assess the clinical effectiveness of a sonographer-led, cardiologist-interpreted stress echocardiography (SE) service in a rapid access stable chest pain clinic (RACPC) setting.
Baseline data was collected prospectively on 768 consecutive patients, referred from the RACPC, who underwent SE between May 2014 and May 2015. Retrospective analysis was performed on follow-up data for outcomes. Among 768 patients (mean age 58 years, 57.8% males) with a mean pre-test probability of coronary artery disease (CAD) of 31%, 675 (88%) underwent SE on the same day as the RACPC consultation. Diagnostic tests were obtained in 749 (97.5%) cases with 62 (8.1%) demonstrating inducible ischemia. Coronary angiography was performed in 61 patients of whom 54 demonstrated flow-limiting CAD (positive predictive value: 88.5%). There was no occurrence of serious adverse events. During a mean follow-up period of 2.5 years, 20 first cardiac events were recorded, of which annualised events in the normal SE group were 0.64% versus 5.8% in patients with an abnormal SE (log rank p < 0.001).
Sonographer-led SE interpreted by a cardiologist is feasible, safe and efficacious. It impacted on the management of patients with appropriate outcomes and may be a cost-efficient and safer alternative to other non-invasive imaging modalities in the RACPC setting.
评估超声心动图医师主导、心脏病专家解读的应激超声心动图(SE)服务在快速通道稳定型胸痛诊所(RACPC)中的临床效果。
前瞻性收集了 2014 年 5 月至 2015 年 5 月间,连续 768 例因 RACPC 就诊而接受 SE 的患者的基线数据。对随访结果进行回顾性分析。768 例患者(平均年龄 58 岁,57.8%为男性)的基线预测试验冠心病(CAD)概率平均为 31%,其中 675 例(88%)在 RACPC 就诊当天接受 SE。749 例(97.5%)获得了诊断性检查,其中 62 例(8.1%)显示有可诱导的缺血。对 61 例患者进行了冠状动脉造影检查,其中 54 例证实为血流受限性 CAD(阳性预测值:88.5%)。未发生严重不良事件。在平均 2.5 年的随访期间,记录到 20 例首次心脏事件,其中正常 SE 组的年化事件发生率为 0.64%,异常 SE 组为 5.8%(对数秩检验 p<0.001)。
由超声心动图医师主导、心脏病专家解读的 SE 是可行、安全且有效的。它对患者的管理产生了影响,对于 RACPC 环境中的其他非侵入性成像方式来说,可能是一种成本效益更高、更安全的替代方法。