Wang Haiqin, Tan Yuyong, Huo Jirong, Liu Deliang
Department of Geriatrics.
Department of Gastroenterology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Medicine (Baltimore). 2019 Feb;98(6):e14484. doi: 10.1097/MD.0000000000014484.
To explore the feasibility and efficacy of submucosal 1-tunnel endoscopic resection (1-tunnel STER) for the treatment of multiple upper gastrointestinal submucosal tumors (GI-SMTs) originating from the muscularis propria (MP) layer.A total of 12 patients with multiple upper GI-SMTs (no less than 2 SMTs) who underwent 1-tunnel STER from April 2013 to October 2017 were included. Clinical data on general characteristics, operation-related parameters, adverse events, and follow-up results were recorded and analyzed.All 12 patients underwent 1-tunnel STER successfully, and the mean operation time was 92.1 ± 40.8 minutes. A total of 30 SMTs were resected, out of which 27 were in the esophagus and 3 were in the stomach. The mean diameter was 15.0 ± 8.2 mm (range, 3-38 mm). All the SMTs were resected en bloc uneventfully. The SMTs comprised 28 leiomyomas and 2 gastric stromal tumors (low risk). No recurrence was noticed during a mean follow-up of 24.9 ± 15.3 months (range, 1-52 months).One-tunnel STER may serve as a feasible and effective technique for the treatment of multiple upper GI-SMTs originating from the MP layer. A large-scale prospective study is warranted for a confirmative conclusion.
探讨黏膜下单隧道内镜切除术（1-tunnel STER）治疗起源于固有肌层（MP）的多发上消化道黏膜下肿瘤（GI-SMTs）的可行性和疗效。纳入2013年4月至2017年10月期间接受1-tunnel STER治疗的12例多发上消化道GI-SMTs（不少于2个SMTs）患者。记录并分析患者的一般特征、手术相关参数、不良事件及随访结果等临床资料。12例患者均成功接受1-tunnel STER治疗，平均手术时间为92.1±40.8分钟。共切除30个SMTs，其中27个位于食管，3个位于胃。平均直径为15.0±8.2mm（范围3-38mm）。所有SMTs均完整切除，过程顺利。SMTs包括28个平滑肌瘤和2个胃间质瘤（低风险）。平均随访24.9±15.3个月（范围1-52个月），未发现复发。单隧道STER可作为治疗起源于MP层的多发上消化道GI-SMTs的一种可行且有效的技术。需要进行大规模前瞻性研究以得出肯定结论。
