Servicio de Enfermedades Autoinmunes, Hospital Clínic, Universitat de Barcelona, Barcelona, España.
Servicio de Enfermedades Autoinmunes, Hospital Clínic, Universitat de Barcelona, Barcelona, España.
Med Clin (Barc). 2019 Jun 21;152(12):495-501. doi: 10.1016/j.medcli.2018.10.030. Epub 2019 Feb 4.
Imaging has become an essential tool in the management of patients with giant cell arteritis. Cranial involvement detected by Doppler ultrasonography is an unquestionable diagnostic finding. Imaging of the aorta and its branches with positron emission tomography, computed tomography angiography or magnetic resonance imaging may also have a role in diagnosis and in the assessment of disease activity and response to treatment, but standardisation and validation are still needed before their widespread use as an outcome measure. Aortic structural damage is associated with increased mortality in giant cell arteritis; therefore, periodic screening is recommended.
影像学检查已成为巨细胞动脉炎患者管理的重要手段。经多普勒超声检查发现的颅外受累是明确的诊断依据。正电子发射断层扫描、计算机断层血管造影或磁共振成像对主动脉及其分支的成像也可能在诊断以及评估疾病活动度和治疗反应方面发挥作用,但在将其广泛用作结局指标之前,仍需要对其进行标准化和验证。主动脉结构损伤与巨细胞动脉炎患者的死亡率增加相关;因此,建议定期筛查。