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大规模筛查以降低乳腺癌死亡率。

Mass screening to reduce mortality from breast cancer.

作者信息

Strax P

机构信息

Strax Breast Cancer Detection Institute, Lauderhill, Florida 33351.

出版信息

Semin Surg Oncol. 1988;4(4):218-20. doi: 10.1002/ssu.2980040404.

Abstract

It is generally agreed that the best and possibly the only means to reduce mortality in breast cancer is to detect the disease in its early, most curable stage. This usually means detection when nodes are negative and often when the lesion is nonpalpable. The best method with which to achieve this goal is periodic examination including clinical study and mammography when the woman is apparently well, as is done in mass screening. This applies today to all women over 40 yr old. A baseline examination at age 35 yr is helpful. Radiation risk is today considered to be minimal, if any, and probably is not even measurable. Cost is important. The dedication of the screening institution is most important in this regard. The chief stumbling block is a lack of motivation on the part of subjects to accept or even demand the examination. This needs to be stimulated through contacts with women directly and with their physicians.

摘要

人们普遍认为,降低乳腺癌死亡率的最佳且可能是唯一的方法是在疾病的早期、最可治愈阶段进行检测。这通常意味着在淋巴结阴性时进行检测,而且常常是在病变无法触及时进行检测。实现这一目标的最佳方法是定期检查,包括临床检查和乳房X光检查,就像在大规模筛查中那样,在女性看起来健康时进行检查。如今,这适用于所有40岁以上的女性。35岁时进行一次基线检查会有所帮助。如今,辐射风险即便存在也被认为是极小的,甚至可能无法测量。成本很重要。在这方面,筛查机构的奉献精神最为重要。主要的绊脚石是受试者缺乏接受甚至要求进行检查的积极性。这需要通过直接与女性及其医生接触来激发。

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