Rahman M A, Hasan M N, Ahmed Q M, Rahim M A, Islam M S
Dr Md Atikur Rahman, Phase-B Resident, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:
Mymensingh Med J. 2019 Jan;28(1):241-244.
Haemophagocytosis encompasses phagocytosis of erythrocytes, leukocytes, platelets and their precursors by macrophages in bone marrow and other tissues. Haemophagocytic lymphohistiocytosis (HLH) usually presents with high fever, pancytopenia, splenomegaly, lymphadenopathy, haemophagocytosis in bone marrow, liver, lymphnodes or CSF. We report coagulase negative Staphylococcus induced HLH in a 16 year old boy presenting with high grade fever, lymphadenopathy, hepatosplenomegaly, pancytopenia with neutropenic sepsis in the department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh on 28th November 2016. He responded to high dose dexamethasone and management of neutropenic sepsis. This might give a guidance in the management of haemophagocytic syndrome at the earliest time to prevent morbidity and mortality.
噬血细胞作用包括骨髓和其他组织中的巨噬细胞对红细胞、白细胞、血小板及其前体细胞的吞噬作用。噬血细胞性淋巴组织细胞增生症（HLH）通常表现为高热、全血细胞减少、脾肿大、淋巴结病、骨髓、肝脏、淋巴结或脑脊液中的噬血细胞现象。我们报告了2016年11月28日在孟加拉国达卡的班加班杜·谢赫·穆吉布医科大学（BSMMU）内科，一名16岁男孩因凝固酶阴性葡萄球菌感染导致HLH，出现高热、淋巴结病、肝脾肿大、全血细胞减少伴中性粒细胞减少性败血症。他对大剂量地塞米松治疗及中性粒细胞减少性败血症的处理有反应。这可能为尽早管理噬血细胞综合征以预防发病和死亡提供指导。
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