Brauns Elisa, Schuind Sophie, Lebrun Laetitia, Inthasot Valentine, Vandergheynst Frédéric
Service de Médecine Interne, CHU Erasme, Brussels, Belgium.
Service de Neurochirurgie, CHU Erasme, Brussels, Belgium.
Eur J Case Rep Intern Med. 2018 Feb 22;5(2):000784. doi: 10.12890/2017_000784. eCollection 2018.
A young woman presented with initial epileptic seizures and multiple 'mass-like' lesions seen on computed tomography and magnetic resonance imaging. Given this presentation and her past medical history, a cerebral biopsy was performed to rule out malignancy, but showed a necrotizing cerebral vasculitis. We describe this case to reinforce the view that primary central nervous system vasculitis (PCNSV) should be considered in the differential diagnosis of a cerebral mass, even if uncommon.
PCNSV may cause a variety of clinical manifestations including seizures.PCNSV lesions can mimic a cerebral mass.Brain biopsy remains the gold standard for the diagnosis of PCNSV, especially to rule out a cancer diagnosis.
一名年轻女性最初出现癫痫发作,计算机断层扫描和磁共振成像显示有多个“肿块样”病变。鉴于此表现及她的既往病史,进行了脑活检以排除恶性肿瘤,但结果显示为坏死性脑血管炎。我们描述此病例以强化这样一种观点,即即使原发性中枢神经系统血管炎(PCNSV)不常见,在脑肿块的鉴别诊断中也应考虑到它。
PCNSV可导致包括癫痫发作在内的多种临床表现。PCNSV病变可类似脑肿块。脑活检仍是PCNSV诊断的金标准,尤其是用于排除癌症诊断。