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腔内三维光学相干断层扫描——一种用于咽鼓管成像的工具?

Intraluminal three-dimensional optical coherence tomography - a tool for imaging of the Eustachian tube?

作者信息

Schuon R, Mrevlje B, Vollmar B, Lenarz T, Paasche G

机构信息

Department of Otorhinolaryngology,Hannover Medical School,Germany.

Trent Cardiac Centre,Nottingham University Hospital NHS Trust,UK.

出版信息

J Laryngol Otol. 2019 Feb;133(2):87-94. doi: 10.1017/S002221511800230X. Epub 2019 Feb 18.

Abstract

OBJECTIVES

The cause of Eustachian tube dysfunction often remains unclear. Therefore, this study aimed to examine the feasibility and possible diagnostic use of optical coherence tomography in the Eustachian tube ex vivo.

METHODS

Two female blackface sheep cadaver heads were examined bilaterally. Three conditions of the Eustachian tube were investigated: closed (resting position), actively opened and stented. The findings were compared (and correlated) with segmented histological cross-sections.

RESULTS

Intraluminal placement of the Eustachian tube with the optical coherence tomography catheter was performed without difficulty. Regarding the limited infiltration depth of optical coherence tomography, tissues can be differentiated. The localisation of the stent was accurate as was the lumen.

CONCLUSION

The application of optical coherence tomography in the Eustachian tube under these experimental conditions is considered to be a feasible, rapid and non-invasive diagnostic method, with possible diagnostic value for determining the luminal shape and superficial lining tissue of the Eustachian tube.

摘要

目的

咽鼓管功能障碍的病因常常不明。因此,本研究旨在探讨光学相干断层扫描在离体咽鼓管中的可行性及可能的诊断用途。

方法

对两只雌性黑脸羊的尸体头部进行双侧检查。研究了咽鼓管的三种状态:闭合(静止位置)、主动开放和置入支架。将这些发现与分段组织学横截面进行比较(并关联)。

结果

使用光学相干断层扫描导管在咽鼓管腔内放置操作并无困难。鉴于光学相干断层扫描的浸润深度有限,可以区分组织。支架的定位以及管腔的定位都很准确。

结论

在这些实验条件下,光学相干断层扫描在咽鼓管中的应用被认为是一种可行、快速且无创的诊断方法,对于确定咽鼓管的管腔形状和表面衬里组织可能具有诊断价值。

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