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发芽的解决方案还是基因的问题:从伊斯兰教视角看人类生殖系基因编辑。

Germ-Inating Solutions or Gene-Rating Problems: An Islamic Perspective on Human Germline Gene Editing.

机构信息

Independent Scholar, University of Oxford, Bolton, UK.

出版信息

J Relig Health. 2020 Aug;59(4):1855-1869. doi: 10.1007/s10943-019-00770-5.

DOI:10.1007/s10943-019-00770-5
PMID:30778792
Abstract

Human germline gene editing (hGGE) poses many questions for the Muslim community. They range from the scientific: is there sufficient evidence that hGGE is better than existing technologies? To the ethical: is the lack of consent an insurmountable hurdle? What is the moral status of the embryo? What effect would hGGE have on societal inequalities? And, most crucially, can hGGE be interdicted on the basis of preventing its ineluctable use in eugenic programming? This paper confronts these issues from a religious perspective basing its judgements and reasoning on traditional sources of Islamic jurisprudence. It concludes that, except in very few instances that must be individual and case-specific, hGGE is not congruent with the tenets of Islam.

摘要

人类生殖系基因编辑(hGGE)给穆斯林社区带来了许多问题。这些问题涉及多个方面,包括科学层面的问题,如:是否有充分的证据表明 hGGE 优于现有技术?以及伦理层面的问题,如:缺乏同意是否是一个不可逾越的障碍?胚胎的道德地位是什么?hGGE 会对社会不平等产生什么影响?最重要的是,能否基于防止其不可避免地用于优生学编程的理由,禁止 hGGE?本文从宗教角度出发,基于伊斯兰教法学的传统渊源来处理这些问题,并得出结论,除非在极少数必须具体问题具体分析的情况下,hGGE 与伊斯兰教教义不符。

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引用本文的文献

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Comparative ethical evaluation of epigenome editing and genome editing in medicine: first steps and future directions.医学中表观基因组编辑与基因组编辑的比较伦理评估:初步步骤与未来方向
J Med Ethics. 2024 May 22;50(6):398-406. doi: 10.1136/jme-2022-108888.
2
Playing God? Religious Perspectives on Manipulating the Genome.扮演上帝?从宗教角度看待基因编辑。
J Relig Health. 2022 Aug;61(4):3192-3218. doi: 10.1007/s10943-022-01497-6. Epub 2022 Jan 13.
3
Researchers views about perceived harms and benefits of gene editing: A study from the MENA region.
研究人员对基因编辑的感知危害和益处的看法:一项来自中东和北非地区的研究。
Heliyon. 2021 Apr 23;7(4):e06860. doi: 10.1016/j.heliyon.2021.e06860. eCollection 2021 Apr.