miR-101 suppresses the development of -rearranged acute myeloid leukemia.
作者信息
Gonzales-Aloy Estrella, Connerty Patrick, Salik Basit, Liu Bing, Woo Andrew J, Haber Michelle, Norris Murray D, Wang Jianlong, Wang Jenny Y
机构信息
Cancer and Stem Cell Biology Group, Children's Cancer Institute, University of New South Wales, Sydney, Australia.
Kids Cancer Alliance, Translational Cancer Research Centre for Kids, Cancer Institute New South Wales, Sydney, Australia.
出版信息
Haematologica. 2019 Jul;104(7):e296-e299. doi: 10.3324/haematol.2018.209437. Epub 2019 Feb 21.
Abstract
摘要
相似文献
1
miR-101 suppresses the development of -rearranged acute myeloid leukemia.
Haematologica. 2019 Jul;104(7):e296-e299. doi: 10.3324/haematol.2018.209437. Epub 2019 Feb 21.
2
Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia.
Clin Cancer Res. 2019 May 1;25(9):2795-2808. doi: 10.1158/1078-0432.CCR-18-1474. Epub 2019 Jan 16.
3
Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.
Cancer Lett. 2016 Mar 28;372(2):157-65. doi: 10.1016/j.canlet.2015.12.032. Epub 2016 Jan 11.
4
The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia.
Cancer Res. 2016 Mar 1;76(5):1158-69. doi: 10.1158/0008-5472.CAN-15-1070. Epub 2015 Dec 1.
5
Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair.
Clin Epigenetics. 2019 Oct 7;11(1):137. doi: 10.1186/s13148-019-0723-0.
6
ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.
Oncotarget. 2017 Apr 18;8(16):26129-26141. doi: 10.18632/oncotarget.15387.
7
The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.
J Hematol Oncol. 2020 Jun 17;13(1):78. doi: 10.1186/s13045-020-00909-y.
8
Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.
J Hematol Oncol. 2016 Mar 12;9:24. doi: 10.1186/s13045-016-0252-7.
9
Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia.
Oncotarget. 2016 May 3;7(18):25208-23. doi: 10.18632/oncotarget.8199.
10
Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML.
Leukemia. 2018 Feb;32(2):499-509. doi: 10.1038/leu.2017.206. Epub 2017 Jun 30.
引用本文的文献
1
Targeting the mTOR Signaling Pathway Through miR-100 and miR-101 in De Novo Acute Myeloid Leukemia: Implications for Therapeutic Intervention.
Cancer Rep (Hoboken). 2025 Aug;8(8):e70264. doi: 10.1002/cnr2.70264.
2
Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML.
Blood. 2024 Jul 4;144(1):84-98. doi: 10.1182/blood.2024024072.
3
Trials and Tribulations of MicroRNA Therapeutics.
Int J Mol Sci. 2024 Jan 25;25(3):1469. doi: 10.3390/ijms25031469.
4
Circulating microRNAs as Potential Biomarkers in Pancreatic Cancer-Advances and Challenges.
Int J Mol Sci. 2023 Aug 28;24(17):13340. doi: 10.3390/ijms241713340.
5
miR-30e-5p regulates leukemia stem cell self-renewal through the Cyb561/ROS signaling pathway.
Haematologica. 2024 Feb 1;109(2):411-421. doi: 10.3324/haematol.2023.282837.
6
Contingent Synergistic Interactions between Non-Coding RNAs and DNA-Modifying Enzymes in Myelodysplastic Syndromes.
Int J Mol Sci. 2022 Dec 16;23(24):16069. doi: 10.3390/ijms232416069.
7
MiR-27a downregulates 14-3-3θ, RUNX1, AF4, and MLL-AF4, crucial drivers of blast transformation in t(4;11) leukemia cells.
Cell Biochem Funct. 2022 Oct;40(7):706-717. doi: 10.1002/cbf.3736. Epub 2022 Aug 18.
8
Down-regulation of HCP5 inhibits cell proliferation, migration, and invasion through regulating EPHA7 by competitively binding miR-101 in osteosarcoma.
Braz J Med Biol Res. 2021 Jan 8;54(2):e9161. doi: 10.1590/1414-431X20209161. eCollection 2021.
9
Downregulation of extracellular vesicle microRNA-101 derived from bone marrow mesenchymal stromal cells in myelodysplastic syndrome with disease progression.
Oncol Lett. 2020 Mar;19(3):2053-2061. doi: 10.3892/ol.2020.11282. Epub 2020 Jan 9.
10
Long non-coding RNA SNHG1 indicates poor prognosis and facilitates disease progression in acute myeloid leukemia.
Biol Open. 2019 Oct 18;8(10):bio046417. doi: 10.1242/bio.046417.
本文引用的文献
1
Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia.
Leukemia. 2016 Aug;30(8):1745-8. doi: 10.1038/leu.2016.24. Epub 2016 Feb 9.
2
GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis.
Blood. 2014 Nov 20;124(22):3284-94. doi: 10.1182/blood-2013-10-532523. Epub 2014 Oct 7.
3
A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells.
Nucleic Acids Res. 2014 Oct 29;42(19):12041-51. doi: 10.1093/nar/gku872. Epub 2014 Sep 26.
4
The role of miR-150 in normal and malignant hematopoiesis.
Oncogene. 2014 Jul 24;33(30):3887-93. doi: 10.1038/onc.2013.346. Epub 2013 Aug 19.
5
Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia.
Blood. 2012 Aug 2;120(5):1107-17. doi: 10.1182/blood-2011-11-394932. Epub 2012 Jun 7.
6
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
Science. 2010 Mar 26;327(5973):1650-3. doi: 10.1126/science.1186624.
7
Exploring complex miRNA-mRNA interactions with Bayesian networks by splitting-averaging strategy.
BMC Bioinformatics. 2009 Dec 10;10:408. doi: 10.1186/1471-2105-10-408.
8
MicroRNA 29b functions in acute myeloid leukemia.
Blood. 2009 Dec 17;114(26):5331-41. doi: 10.1182/blood-2009-03-211938. Epub 2009 Oct 22.
9
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Science. 2008 Dec 12;322(5908):1695-9. doi: 10.1126/science.1165395. Epub 2008 Nov 13.
10
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
Blood. 2008 Mar 15;111(6):3183-9. doi: 10.1182/blood-2007-07-098749. Epub 2008 Jan 10.
Zotero 插件