Imai Fuminobu, Momino Kanae, Katsuki Fujika, Horikoshi Masaru, Furukawa Toshi A, Kondo Naoto, Toyama Tatsuya, Yamaguchi Takuhiro, Akechi Tatsuo
Division of Psycho-Oncology and Palliative Care, Nagoya City University Hospital, Mizuho-cho, Mizuho-ku, Nagoya, Japan.
Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho-cho, Mizuho-ku, Nagoya, Japan.
Jpn J Clin Oncol. 2019 Jun 1;49(6):537-544. doi: 10.1093/jjco/hyz005.
The purpose of this study was to investigate a newly developed smartphone problem-solving therapy (PST) application's feasibility and preliminary effectiveness for reducing fear of cancer recurrence (FCR) among breast cancer survivors.
Female disease-free breast cancer survivors aged 20-49 years who were more than 6 months post-breast surgery participated in the study. The patients received the smartphone PST using an iPhone or iPad for 8 weeks. The feasibility of the intervention program was evaluated using the overall participation rate, the percentage of survivors who expressed interest in the intervention, and the percentage of completion of the study. Patients were also asked to complete the Concern About Recurrence Scale (CARS) as a primary outcome at baseline, 4 weeks and 8 weeks.
A total of 38 patients participated in this study. The overall participation and completion rates in the study were 47.1% and 97.4%, respectively. The overall fear assessed by CARS was significantly reduced at 8 weeks compared with baseline. A pairwise comparison showed a significant decrease from 4 weeks to 8 weeks and from baseline to 8 weeks.
Smartphone PST, a novel brief intervention to reduce FCR, was well accepted by breast cancer survivors and yielded a favorable effect on FCR. The efficacy of this newly developed smartphone PST needs to be confirmed in a future well-designed randomized controlled trial.
本研究旨在调查一种新开发的智能手机问题解决疗法(PST)应用程序在降低乳腺癌幸存者癌症复发恐惧(FCR)方面的可行性和初步效果。
年龄在20 - 49岁、乳腺癌手术后超过6个月且无疾病的女性乳腺癌幸存者参与了本研究。患者使用iPhone或iPad接受智能手机PST治疗8周。通过总体参与率、表示对干预感兴趣的幸存者百分比以及研究完成百分比来评估干预项目的可行性。患者还被要求在基线、4周和8周时完成癌症复发担忧量表(CARS)作为主要结局指标。
共有38名患者参与了本研究。研究的总体参与率和完成率分别为47.1%和97.4%。与基线相比,8周时通过CARS评估的总体恐惧显著降低。两两比较显示从4周到8周以及从基线到8周均有显著下降。
智能手机PST作为一种减少FCR的新型简短干预措施,受到乳腺癌幸存者的良好接受,并对FCR产生了有利影响。这种新开发的智能手机PST的疗效需要在未来精心设计的随机对照试验中得到证实。