Department of Ophthalmology Sanggye Paik Hospital, College of Medicine, Inje University of Korea, Seoul, Republic of Korea.
Department of Ophthalmology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Republic of Korea.
Ocul Immunol Inflamm. 2020;28(2):182-187. doi: 10.1080/09273948.2018.1562557. Epub 2019 Feb 22.
: To compare meibomian gland (MG) imaging findings and lipid layer thickness (LLT) between patients with primary Sjögren syndrome (SS) dry eyes (DE) and non-SS DE.: A total of 60 patients-30 with SS DE and 30 with non-SS DE were evaluated. Infrared image findings of MGs and LLT were assessed using the LipiView II interferometer.: The maximum LLT was significantly lower in the SS DE group. SS DE exhibited significantly higher MG dropout compared to the non-SS DE. Average and maximal LLT showed significant negative correlations with MG dropout in both groups (p<0.05). Conjunctival staining scores showed significant correlations with average and maximum LLT and MG dropout values in the SS DE group (p<0.05).: These findings suggest that the new interferometer will be useful in understanding the pathophysiology of SS DE.
: 比较原发性干燥综合征 (SS) 干眼 (DE) 患者和非 SS DE 患者的睑板腺 (MG) 成像和脂质层厚度 (LLT)。共评估了 60 名患者,其中 30 名患有 SS DE,30 名患有非 SS DE。使用 LipiView II 干涉仪评估 MGs 的红外图像和 LLT。SS DE 组的最大 LLT 明显较低。SS DE 的 MG 脱落明显高于非 SS DE。两组的平均和最大 LLT 与 MG 脱落呈显著负相关(p<0.05)。SS DE 组的结膜染色评分与平均和最大 LLT 以及 MG 脱落值呈显著相关(p<0.05)。这些发现表明,新的干涉仪将有助于理解 SS DE 的病理生理学。