Laboratory of Epidemiology of Federal University of Espírito Santo, Vitória/ES, Brazil.
Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, CA, United States of America.
PLoS One. 2019 Feb 22;14(2):e0212617. doi: 10.1371/journal.pone.0212617. eCollection 2019.
Tuberculosis incidence is disproportionately high among people in poverty. Cash transfer programs have become an important strategy in Brazil fight inequalities as part of comprehensive poverty alleviation policies. This study was aimed at assessing the effect of being a beneficiary of a governmental cash transfer program on tuberculosis (TB) treatment cure rates.
We conducted a longitudinal database study including people ≥18 years old with confirmed incident TB in Brazil in 2015. We treated missing data with multiple imputation. Poisson regression models with robust variance were carried out to assess the effect of TB determinants on cure rates. The average effect of being beneficiary of cash transfer was estimated by propensity-score matching.
In 2015, 25,084 women and men diagnosed as new tuberculosis case, of whom 1,714 (6.8%) were beneficiaries of a national cash transfer. Among the total population with pulmonary tuberculosis several determinants were associated with cure rates. However, among the cash transfer group, this association was vanished in males, blacks, region of residence, and people not deprived of their freedom and who smoke tobacco. The average treatment effect of cash transfers on TB cure rates, based on propensity score matching, found that being beneficiary of cash transfer improved TB cure rates by 8% [Coefficient 0.08 (95% confidence interval 0.06-0.11) in subjects with pulmonary TB].
Our study suggests that, in Brazil, the effect of cash transfer on the outcome of TB treatment may be achieved by the indirect effect of other determinants. Also, these results suggest the direct effect of being beneficiary of cash transfer on improving TB cure rates.
结核病在贫困人口中的发病率不成比例地高。现金转移计划已成为巴西不平等斗争的重要策略,是全面减贫政策的一部分。本研究旨在评估作为政府现金转移计划的受益者对结核病(TB)治疗治愈率的影响。
我们进行了一项纵向数据库研究,纳入了 2015 年巴西确诊的 18 岁及以上新发结核病患者。我们使用多重插补处理缺失数据。采用稳健方差的泊松回归模型评估结核病决定因素对治愈率的影响。通过倾向评分匹配估计成为现金转移受益者的平均效应。
2015 年,共诊断出 25084 名男性和女性新结核病病例,其中 1714 名(6.8%)为国家现金转移的受益者。在所有肺结核患者中,有几个决定因素与治愈率有关。然而,在现金转移组中,这种关联在男性、黑人、居住地和未被剥夺自由且不吸烟的人群中消失了。基于倾向评分匹配的现金转移对结核病治愈率的平均治疗效果发现,成为现金转移的受益者使结核病治愈率提高了 8%[系数 0.08(95%置信区间 0.06-0.11),在患有肺结核的人群中]。
我们的研究表明,在巴西,现金转移对结核病治疗结果的影响可能是通过其他决定因素的间接效应实现的。此外,这些结果表明成为现金转移受益者直接提高了结核病治愈率。