Otolaryngology-Head & Neck Surgery, Sunnybrook Health Science Center, Toronto, ON, Canada.
Surgery, Duke University Medical Center, DUMC Box 3805, Durham, NC, USA.
Dysphagia. 2019 Dec;34(6):904-915. doi: 10.1007/s00455-019-09987-8. Epub 2019 Feb 23.
(1) To examine the association between vocal fold paresis/paralysis (VFP) and poor swallowing outcomes in a thoracic surgery cohort at the population level, and (2) to assess utilization of ENT/speech-language pathology intervention in these cases. The National Inpatient Sample (NIS) represents a 20% stratified sample of discharges from US hospitals. Using ICD-9 codes, discharges undergoing general thoracic surgical procedures between 2008 and 2013 were identified in the NIS. Sub-cohorts of discharges with VFP and those who utilized ENT/SLP services were also identified. Weighted logistic regression models were used to compare binary outcomes such as dysphagia, aspiration pneumonia, and other complications; generalized linear models with generalized estimating equations (GEE) were used to compare total hospital costs and length of stay (LOS). We identified a weighted estimate of 673,940 discharges following general thoracic surgery procedures. The weighted frequency of VFP was 3738 (0.55%). Compared to those without VFP, patients who discharged with VFP had increased odds of dysphagia (6.56, 95% CI 5.07-8.47), aspiration pneumonia (2.54, 95% CI 1.74-3.70), post-operative tracheotomy (3.10, 95% CI 2.16-4.45), and gastrostomy tube requirement (2.46, 95% CI 1.66-3.64). Discharges with VFP also had a longer length of stay and total hospital costs. Of the discharges with VFP, 15.7% received ENT/SLP intervention. VFP after general thoracic procedures is associated with negative swallowing-related health outcomes and higher costs. Despite these negative impacts, most patients with VFP do not receive ENT/SLP intervention, identifying a potential opportunity for improving adverse swallowing-related outcomes.
(1)在人群水平上,检查胸外科队列中声带麻痹/瘫痪(VFP)与吞咽不良结局之间的关联,并(2)评估这些病例中耳鼻喉科/言语病理学干预的利用情况。国家住院患者样本(NIS)代表美国医院出院患者的 20%分层样本。使用 ICD-9 代码,在 NIS 中确定了 2008 年至 2013 年间进行普通胸外科手术的出院患者。还确定了 VFP 出院患者和使用耳鼻喉科/言语病理学服务的出院患者亚队列。使用加权逻辑回归模型比较吞咽困难、吸入性肺炎和其他并发症等二项结局;使用广义估计方程(GEE)的广义线性模型比较总住院费用和住院时间(LOS)。我们确定了普通胸外科手术后出院的加权估计值为 673940 例。VFP 的加权频率为 3738(0.55%)。与无 VFP 的患者相比,患有 VFP 的患者发生吞咽困难的几率更高(6.56,95%CI 5.07-8.47)、吸入性肺炎(2.54,95%CI 1.74-3.70)、术后气管切开术(3.10,95%CI 2.16-4.45)和胃造口管需求(2.46,95%CI 1.66-3.64)。患有 VFP 的患者住院时间和总住院费用也更长。患有 VFP 的出院患者中,有 15.7%接受了耳鼻喉科/言语病理学干预。普通胸外科手术后的 VFP 与负面的吞咽相关健康结局和更高的成本相关。尽管存在这些负面影响,但大多数患有 VFP 的患者并未接受耳鼻喉科/言语病理学干预,这为改善不良吞咽相关结局提供了潜在机会。